About the Biomolecular and Computational Toxicology Division
On This Page:
What We Do
Our Research
Management
Branches
Main Office Location
What We Do
The Biomolecular and Computational Toxicology Division (BCTD) supports the Agency’s mission by expanding and refining the development and use of new approach methods for evaluating chemicals for health effects. BCTD develops and uses high-throughput assays, complex cell culture systems, alternative species models and computational and informatics approaches to transform the components of chemical risk assessment with a focus on human health. BCTD research aims to broaden the acceptance and implementation of these new approaches in support of regulatory decisions.
Our Research
- ToxCast
- Toxicology in the 21st Century Federal Consortium
- Understanding Chemical Interaction with Biological Systems
- Developmental Neurotoxicity
Management
Katie Paul Friedman, Acting Director
- Email: Paul-Friedman.Katie@epa.gov
Daniel Hallinger, Associate Director
- Email: hallinger.daniel@epa.gov
Branches
- Advanced Experimental Toxicology Models Branch (AETMB): John Cowden, Branch Chief
AETMB develops and utilizes complex cell culture systems and alternative species models to predict the tissue, organ, and organism-level effects of chemicals. - Computational Toxicology and Bioinformatics Branch (CTBB): Tim Buckley, Acting Branch Chief
CTBB utilizes computational and informatics approaches to analyze and integrate data from high-throughput toxicity assays, complex culture models, alternative species, toxicokinetics, and chemistry to predict adverse effects of chemicals in human and animal models. - Rapid Assay Development Branch (RADB): Kimberly Slentz-Kesler, Branch Chief
RADB develops the next generation of high-throughput toxicity assays to comprehensively cover the potential molecular and phenotypic responses results from chemical exposure and fill gaps in biological pathways and processes not addressed using existing assays.