Risk Evaluation for 1,1,2-Trichloroethane

In June 2026, EPA released the draft human health and environmental hazard assessment and exposure assessment for 1,1,2-trichloroethane. EPA designated 1,1,2-trichloroethane as a high priority chemical in December 2019 and the chemical is currently undergoing risk evaluation.

Find other information about other chemicals undergoing risk evaluations under TSCA. 

On this page:

• What is 1,1,2-Trichloroethane?
• Uses of 1,1,2-Trichloroethane
• Recent Activities and Opportunities for Public Comment
• Draft Supporting Documents

What is 1,1,2-Trichloroethane?

1,1,2-Trichloroethane (CASRN 79-00-5) is a colorless liquid, with a sweet odor, and it is highly flammable. The primary use of 1,1,2-trichloroethane is in plastic and petrochemical manufacturing. Information from the 2016 Chemical Data Reporting (CDR) for 1,1,2-trichloroethane indicates the reported production volume is between 100 and 250 million lbs/year.

Uses of 1,1,2-Trichloroethane

In the final scope, EPA identified conditions of use associated with the manufacturing (including importing); processing; distribution; industrial, commercial and consumer uses; and disposal of 1,1,2-trichloroethane, for example:

• In plastic, petrochemical, and other chemical product and preparation manufacturing;
• In industrial adhesives and sealants; and
• As a laboratory chemical.

The above listed conditions of use are ways that a person or the environment could be potentially exposed to this chemical. However, when conducting a risk evaluation, EPA also considers the hazards (i.e. health effects or environmental impacts) that could occur from coming in contact with a chemical.

Recent Activities and Opportunities for Public Comment

In June 2026, EPA released the draft human health and environmental hazard assessment and exposure assessment for peer review by the Science Advisory Committee on Chemicals (SACC).  Upon publication of the Federal Register notice, EPA will accept public comments on these documents in the peer review docket EPA-HQ-OPPT-2026-2246 on www.regulations.gov until July 23, 2026. These documents, along with the draft risk evaluations for these chemicals, will also be available for public comment in separate TSCA dockets later this year.

In August 2020, EPA published a final scope document outlining the hazards, exposures, conditions of use, and the potentially exposed or susceptible subpopulations the agency expects to consider in its risk evaluation. The agency released the draft scope in April 2020 and took public comments on the draft document.

• Read the final scope of the risk evaluation for this chemical and EPA’s response to comments on the draft scope.
• View the docket for this chemical, EPA-HQ-OPPT-2018-0421 on www.regulations.gov.

As EPA continues to move through the risk evaluation process there will be additional opportunities for public comment, including a public comment period on the draft risk evaluation. In addition to public comment periods, EPA will continue to engage with stakeholders as it refines the risk evaluation and stakeholders should reach out to EPA via the staff contact to engage with the agency.

Draft Supporting Documents

Read a pre-publication of the Federal Register Notice and view the supporting documents in EPA-HQ-OPPT-2026-2246.  

• Draft Chemistry, Fate, Release, and Exposure Assessment for 1,1,2-Trichloroethane (pdf) (9.35 MB)
• Draft Human Health and Environmental Hazard Assessment for 1,1,2-Trichloroethane (pdf) (5.19 MB)
• Draft Systematic Review Protocol for 1,1,2-Trichloroethane (pdf) (1.99 MB)
• Draft Data Quality Evaluation and Data Extraction Information for Physical and Chemical Properties for 1,1,2-Trichloroethane (pdf) (715.46 KB)
• Draft Data Quality Evaluation and Data Extraction Information for Environmental Fate and Transport for 1,1,2-Trichloroethane (pdf) (681.18 KB)
• Draft Data Quality Evaluation and Data Extraction Information for Environmental Release and Occupational Exposure for 1,1,2-Trichloroethane (pdf) (976.81 KB)
• Draft Data Quality Evaluation Information for Dermal Absorption for 1,1,2-Trichloroethane (pdf) (515.6 KB)
• Draft Data Quality Evaluation Information for General Population, Consumer, and Environmental Exposure for 1,1,2-Trichloroethane (pdf) (1.03 MB)
• Draft Data Extraction Information for General Population, Consumer, and Environmental Exposure for 1,1,2-Trichloroethane (pdf) (188.76 KB)
• Draft Data Quality Evaluation Information for Human Health Hazard Epidemiology for 1,1,2-Trichloroethane (pdf) (1.21 MB)
• Draft Data Quality Evaluation Information for Human Health Hazard Animal Toxicology for 1,1,2-Trichloroethane (pdf) (1.71 MB)
• Draft Data Quality Evaluation Information for Environmental Hazard for 1,1,2-Trichloroethane (pdf) (1.33 MB)
• Draft Data Extraction Information for Environmental Hazard and Human Health Hazard Animal Toxicology and Epidemiology for 1,1,2-Trichloroethane (pdf) (1.04 MB)

Additional technical support files for the draft risk evaluation of 1,1,2-trichloroethane (zip)