Risk Evaluation for 1,1,2-Trichloroethane

In July 2026, EPA released the draft risk evaluation and associated technical support documents for 1,1,2-trichloroethane under the Toxic Substances Control Act (TSCA) for public comment. EPA designated 1,1,2-trichloroethane as a high priority chemical in December 2019 and the chemical is currently undergoing risk evaluation.

EPA will accept public comments on the draft risk evaluation for 60 days in the TSCA docket (EPA-HQ-OPPT-2018-0421) at www.regulations.gov.

Find other information about other chemicals undergoing risk evaluations under TSCA. 

On this page:

• What is 1,1,2-Trichloroethane?
• Draft Risk Evaluation for 1,1,2-Trichloroethane
• Draft Risk Evaluation and Supporting Documents

What is 1,1,2-Trichloroethane?

1,1,2-Trichloroethane (CASRN 79-00-5) is a colorless liquid, with a sweet odor, and it is highly flammable. The primary use of 1,1,2-trichloroethane is in plastic and petrochemical manufacturing. Information from the 2016 Chemical Data Reporting (CDR) for 1,1,2-trichloroethane indicates the reported production volume is between 100 and 250 million lbs/year.

Draft Risk Evaluation for  1,1,2-Trichloroethane

EPA's draft risk evaluation for 1,1,2-trichloroethane identifies unreasonable risk to workers driven by inhalation and dermal exposures across multiple conditions of use. The draft risk evaluation did not find unreasonable risk to consumers, the general population, or the environment. 

In the draft evaluation, EPA used chemical-specific monitoring data, exposure modeling, and the best available scientific information to assess possible exposure for workers (inhalation and skin contact), consumers, and the general population (including environmental releases to air and water). EPA also evaluated potential risks to aquatic and terrestrial organisms and did not identify unreasonable risk to the environment. 

EPA will move quickly, after peer review and public comment, to finalize the risk evaluation. Should EPA continue to find unreasonable risk, EPA will then propose risk management actions under TSCA to reduce or eliminate unsafe workplace exposures.

EPA emphasizes that this evaluation is draft and does not represent a final Agency determination regarding the risks posed by this chemical. The findings and conclusions may change based on feedback received during the public comment period. Additionally, the release of a draft evaluation does not alter or impact any existing protections, regulations, or risk management measures currently in place for this chemical. All current safeguards remain in place.

Draft Supporting Documents

Read the Federal Register Notice and view the supporting documents in EPA-HQ-OPPT-2018-0421.  

• Draft Risk Evaluation for 1,1,2-Trichloroethane (pdf) (4.98 MB)
• Draft Chemistry, Fate, Release, and Exposure Assessment for 1,1,2-Trichloroethane (pdf) (9.35 MB)
• Draft Human Health and Environmental Hazard Assessment for 1,1,2-Trichloroethane (pdf) (5.19 MB)
• Draft Systematic Review Protocol for 1,1,2-Trichloroethane (pdf) (1.99 MB)
• Draft Data Quality Evaluation and Data Extraction Information for Physical and Chemical Properties for 1,1,2-Trichloroethane (pdf) (715.46 KB)
• Draft Data Quality Evaluation and Data Extraction Information for Environmental Fate and Transport for 1,1,2-Trichloroethane (pdf) (681.18 KB)
• Draft Data Quality Evaluation and Data Extraction Information for Environmental Release and Occupational Exposure for 1,1,2-Trichloroethane (pdf) (976.81 KB)
• Draft Data Quality Evaluation Information for Dermal Absorption for 1,1,2-Trichloroethane (pdf) (515.6 KB)
• Draft Data Quality Evaluation Information for General Population, Consumer, and Environmental Exposure for 1,1,2-Trichloroethane (pdf) (1.03 MB)
• Draft Data Extraction Information for General Population, Consumer, and Environmental Exposure for 1,1,2-Trichloroethane (pdf) (188.76 KB)
• Draft Data Quality Evaluation Information for Human Health Hazard Epidemiology for 1,1,2-Trichloroethane (pdf) (1.21 MB)
• Draft Data Quality Evaluation Information for Human Health Hazard Animal Toxicology for 1,1,2-Trichloroethane (pdf) (1.71 MB)
• Draft Data Quality Evaluation Information for Environmental Hazard for 1,1,2-Trichloroethane (pdf) (1.33 MB)
• Draft Data Extraction Information for Environmental Hazard and Human Health Hazard Animal Toxicology and Epidemiology for 1,1,2-Trichloroethane (pdf) (1.04 MB)

Additional technical support files for the draft risk evaluation of 1,1,2-trichloroethane (zip)