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  2. Children's Health

Children’s Health Risk Assessment Tools and Guidance

Related Resources

  • Risk Assessment
  • Children's Health Research
  • One Health

EPA scientists have a suite of guidance, frameworks, and tools to help public health officials, state, tribal, and local governments, and others make sound decisions that advance healthy and prosperous communities. These resources can also be used to ensure that children’s environmental health is an explicit part of decision-making.

On this page:
  • Guidance and Frameworks
  • Tools

Guidance and Frameworks

  • Exposure Factors Handbook (including updated child-specific values) (2011-2019)
  • Guidelines for Preparing Economic Analyses - Chapter 10 (2014)
  • Child-Specific Exposure Scenarios Examples (2014)
  • A Framework for Assessing Health Risk of Environmental Exposures to Children (2006)
  • Guidance on Selecting Age Groups for Monitoring and Assessing Childhood Exposures to Environmental Contaminants (2005)
  • Supplemental Guidance for Assessing Susceptibility from Early-Life Exposure to Carcinogens (2005)
  • Guidelines for Developmental Toxicity Risk Assessment (1991)
  • Guidelines for Reproductive Toxicity Risk Assessment (1996)

Tools

ToolDescription
America's Children and the Environment (ACE)ACE is EPA's report presenting data on children's environmental health. ACE brings together information from a variety of sources to provide national indicators and related information on the environment and children's health.
All Ages Lead Model (AALM)AALM predicts lead concentration in body tissues and organs of hypothetical individuals, based on a simulated lifetime of lead exposure.
ChemExpoChemExpo is an interactive web application for exploring chemical data, curated from public documents, relevant to exposure assessment. ChemExpo currently surfaces data collected by EPA about how chemicals are used in commerce and how they occur in consumer and industrial products.
CompTox Chemicals DashboardThe CompTox Chemicals Dashboard provides public access to chemical data. It is a widely used resource for chemistry, toxicity, and exposure information for over a million chemicals.
Consumer Exposure Model (CEM)CEM contains a combination of models and default parameters that are used to estimate inhalation, dermal, and oral exposures to consumer products and articles for a variety of use categories.
Exposure Toolbox (Expo-Box)Web-based compendium of over 800 exposure assessment tools that provides links to exposure assessment databases, models, and references.
ExpoKidsExpoKids is a tool that helps scientists and researchers explore a diverse set of children’s health risk assessment and management inquiries by visually depicting the impact of aggregate exposure to contaminants via the oral route to children throughout their lives.
Integrated Exposure Uptake Biokinetic Model for Lead in Children (IEUBK)The IEUBK model is a software package that utilizes four modules (exposure, uptake, biokinetic, and probability distribution) to estimate blood lead (Pb) levels in children who are exposed to Pb-contaminated media.
Stochastic Human Exposure and Dose Simulation Model for Multimedia, Dietary, Residential, and High Throughput (SHEDS)SHEDS is a collection of probabilistic models that can estimate chemical exposures encountered in everyday activities.

Children's Health

  • What You Can Do
    • Children Are Not Little Adults
  • Children's Health Protection Where You Live
  • Childhood Lifestages
  • Healthcare Provider Resources
  • Children's Health Protection Advisory Committee
  • Children's Health Outreach
  • Children's Health Guidance and Tools
Contact Us about Children's Health
Contact Us about Children's Health to ask a question, provide feedback, or report a problem.
Last updated on July 15, 2025
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