Endocrine Disruptor Screening Program Tier 1 Screening Determinations and Associated Data Evaluation Records

The table below contains a collection of documents that present Endocrine Disruptor Screening Program (EDSP) Tier 1 Screening determinations (or weight-of-evidence (WoE) assessments) and associated data evaluation records (DERs) for 52 Tier 1 chemicals as of September 23, 2015. EPA is recommending additional testing, known as Tier 2 testing, for 18 chemicals highlighted in green in the table. View the additional tests required for each chemical.

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Chemical Name CAS Number Docket Number EDSP Tier 1 Screening Determinations/WoE Assessments Associated Data Evaluation Records (DERs)
2,4-D 94-75-7 EPA-HQ-OPP-2012-0330  2,4-D EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF) (221 pp, 6,644 K, About PDF) 2,4-D: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(221 pp, 6,489 K, About PDF)
Abamectin 71751-41-2 EPA-HQ-OPP-2013-0360 Abamectin EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(61 pp, 1,013y K, About PDF) Abamectin: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(252 pp, 8,541  K, About PDF)
Acephate 30560-19-1 EPA-HQ-OPP-2008-0915 Acephate EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(59 pp, 1,006 K, About PDF) Acephate: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(283 pp, 8,219 K, About PDF)
Acetone 67-64-1 EPA-HQ-OPP-2009-0634 Acetone EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(41 pp, 907 K, About PDF) Acetone: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(237 pp, 8,504 K, About PDF)
Atrazine 1912-24-9 EPA-HQ-OPP-2013-0266 Atrazine EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(167 pp, 1,572 K, About PDF) Atrazine: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(59 pp, 1,083 K, About PDF)
Benfluralin 1861-40-1 EPA-HQ-OPP-2011-0931 Benfluralin EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(61 pp, 1,025 K, About PDF) Benfluralin: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(300 pp, 7,995 K, About PDF)
Bifenthrin 82657-04-3 EPA-HQ-OPP-2010-0384 Bifenthrin EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(67pp, 1,051 K, About PDF) Bifenthrin: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(320 pp, 8,542 K, About PDF)
Captan 133-06-2 EPA-HQ-OPP-2013-0296 Captan EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(59 pp, 1,011 K, About PDF) Captan: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(303 pp, 9,027 K, About PDF)
Carbaryl 63-25-2 EPA-HQ-OPP-2010-0230 Carbaryl EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(70 pp, 1,041 K, About PDF) Carbaryl: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(149 pp, 5,716 K, About PDF)
Carbofuran 1563-66-2 EPA-HQ-OPP-2009-0634 Carbofuran EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(237 pp, 8,707 K, About PDF) Carbofuran: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(260 pp, 8,707 K, About PDF)
Chlorothalonil 1897-45-6 EPA-HQ-OPP-2011-0840 Chlorothalonil EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(69 pp, 1,056 K, About PDF) Chlorothalonil: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(260 pp, 10,213K,  About PDF)
Chlorpyrifos 2921-88-2 EPA-HQ-OPP-2008-0850 Chlorpyrifos EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(82 pp, 1,116 K, About PDF) Chlorpyrifos: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(289 pp, 8,319 K, About PDF)
Cyfluthrin 68359-37-5 EPA-HQ-OPP-2010-0684 Cyfluthrin EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(76 pp, 1,111 K, About PDF) Cyfluthrin: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(285 pp, 1,0326 K, About PDF)
Cypermethrin 52315-07-8 EPA-HQ-OPP-2012-0167 Cypermethrin EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(72 pp, 1,095 K, About PDF) Cypermethrin: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(223 pp, 5,244y K, About PDF)
DCPA 1861-32-1 EPA-HQ-OPP-2011-0374 DCPA EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(52 pp, 963 K, About PDF) DCPA: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(321 pp, 9.951 K, About PDF)
Diazinon 333-41-5 EPA-HQ-OPP-2008-0351 Diazinon EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(71 pp, 1,062 K, About PDF) Diazinon: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(281 pp, 8,365 K, About PDF)
Dichlobenil 1194-65-6 EPA-HQ-OPP-2012-0395 Dichlobenil EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(60 pp, 1,042 K, About PDF) Dichlobenil: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(331 pp,7,294 K, About PDF)
Dimethoate 60-51-5 EPA-HQ-OPP-2009-0059- Dimethoate EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(71 pp, 1,117 K, About PDF) Dimethoate: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(225 pp, 6,327 K, About PDF)
EPTC 759-94-4 EPA-HQ-OPP-2012-0720 EPTC EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(63 1,022, K, About PDF) EPTC: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(310 pp, 7,136 K, About PDF)
Esfenvalerate 66230-04-4 EPA-HQ-OPP-2009-0301 Esfenvalerate EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(70 pp, 1,042 K, About PDF) Esfenvalerate: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(206 pp, 8,882 K, About PDF)
Ethoprop 13194-48-4 EPA-HQ-OPP-2008-0560 Ethoprop EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(67 pp, 1,000 K, About PDF) Ethoprop: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(258 pp, 11,504 K, About PDF)
Fenbutatin oxide 13356-08-6 EPA-HQ-OPP-2009-0841 Fenbutatin oxide EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(54 pp, 960 K, About PDF) Fenbutatin oxide: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(287 pp, 11,479 K, About PDF)
Flutolanil 66332-96-5 EPA-HQ-OPP-2008-0148 Flutolanil EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(56 pp, 954 K, About PDF) Flutolanil: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(270 pp, 9,039 K, About PDF)
Folpet 133-07-3 EPA-HQ-OPP-2012-0859 Folpet EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(56 pp, 962 K, About PDF) Folpet: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(311 pp, 10,459 K, About PDF)
Gardona (cis-isomer) / Tetrachlorvinphos 22248-79-9 EPA-HQ-OPP-2008-0316 Gardona (cis-isomer) / Tetrachlorvinphos EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(66 pp, 1,014 K, About PDF) Gardona (cis-isomer) / Tetrachlorvinphos: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(263 pp, 45,80 K, About PDF)
Glyphosate 1071-83-6 EPA-HQ-OPP-2009-0361 Glyphosate EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(70 pp, 1042 K, About PDF) Glyphosate: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(278 pp, 10,390 K, About PDF)
Imidacloprid 138261-41-3 EPA-HQ-OPP-2008-0844 Imidacloprid EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(70 pp, 1,021 K, About PDF) Imidacloprid: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(273 pp, 9,834 K, About PDF)
Iprodione 36734-19-7 EPA-HQ-OPP-2012-0392 Iprodione EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(74 pp, 1,039 K, About PDF) Iprodione: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(211 pp, 4,138 K, About PDF)
Isophorone 78-59-1 EPA-HQ-OPP-2009-0634 Isophorone EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(51 pp, 886 K, About PDF) Isophorone: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(308 pp, 10,150 K, About PDF)
Linuron 330-55-2 EPA-HQ-OPP-2010-0228 Linuron EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(101 pp, 1,158 K, About PDF) Linuron: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(124 pp, 4,903 K, About PDF)
Malathion 121-75-5 EPA-HQ-OPP-2009-0317 Malathion EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(82 pp, 1,144 K, About PDF) Malathion: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(294 pp, 5,265 K, About PDF)
Metalaxyl 57837-19-1 EPA-HQ-OPP-2009-0863 Metalaxyl EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(59 pp, 992 K, About PDF) Metalaxyl: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(292 pp, 4,096 K, About PDF)
Methomyl 16752-77-5 EPA-HQ-OPP-2010-0751 Methomyl EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(62 pp, 1,023 K, About PDF) Methomyl: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(241 pp, 5,649 K, About PDF)
Metolachlor 51218-45-2 EPA-HQ-OPP-2014-0772 Metolachlor EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(69 pp, 1,039 K, About PDF) Metolachlor: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(288 pp, 3,993 K, About PDF)
Metribuzin 21087-64-9 EPA-HQ-OPP-2012-0487 Metribuzin EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(57 pp, 976 K, About PDF) Metribuzin: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(205 pp, 3,083 K, About PDF)
MGK 264 113-48-4 EPA-HQ-OPP-2012-0415 MGK 264 EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(57, 984 K, About PDF) MGK 264: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(242 pp, 9,430 K, About PDF)
Myclobutanil 88671-89-0 EPA-HQ-OPP-2015-0053 Myclobutanil EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(65 pp, 1,030 K, About PDF) Myclobutanil: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(317 pp, 9,239 K, About PDF)
Norflurazon 27314-13-2 EPA-HQ-OPP-2012-0565 Norflurazon EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(62 pp, 1,013 K, About PDF) Norflurazon: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(344 pp, 10,343 K, About PDF)
O-phenylphenol 90-43-7 EPA-HQ-OPP-2013-0524 O-phenylphenol EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(64 pp, 1,011 K, About PDF) O-phenylphenol: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(281 pp, 7,933 K, About PDF)
Oxamyl 23135-22-0 EPA-HQ-OPP-2010-0028 Oxamyl EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(56 pp, 962 K, About PDF) Oxamyl: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(241 pp, 9,604 K, About PDF)
PCNB 82-68-8 EPA-HQ-OPP-2009-0634 PCNB EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(70 pp, 1,064 K, About PDF) PCNB: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(207 pp, 4,452 K, About PDF)
Permethrin 52645-53-1 EPA-HQ-OPP-2011-0039 Permethrin EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(75 pp, 1,093 K, About PDF) Permethrin: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(206 pp, 3,685 K, About PDF)
Phosmet 732-11-6 EPA-HQ-OPP-2009-0316 Phosmet EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(3 pp, 704 K, About PDF) Phosmet: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(260 pp, 5,676 K, About PDF)
Piperonyl butoxide 51-03-6 EPA-HQ-OPP-2010-0498 Piperonyl butoxide EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(62 pp, 972 K, About PDF) Piperonyl butoxide: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(252 pp, 5,544 K, About PDF)
Propargite 2312-35-8 EPA-HQ-OPP-2014-0131 Propargite EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(3 pp, 599 K, About PDF) Propargite: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(307 pp, 9,225 K, About PDF)
Propiconazole 60207-90-1 EPA-HQ-OPP-2009-0634 Propiconazole EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(87pp, 1,113 K, About PDF) Propiconazole: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(154 pp, 4,108 K, About PDF)
Propyzamide 23950-58-5 EPA-HQ-OPP-2009-0326 Propyzamide EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(75 pp, 1,108 K, About PDF) Propyzamide: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(285 8,102 K, About PDF)
Pyriproxyfen 95737-68-1 EPA-HQ-OPP-2011-0677 Pyriproxyfen EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(41 pp, 8,852 K, About PDF) Pyriproxyfen: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)281 pp, 9,364 K, About PDF)
Simazine 122-34-9 EPA-HQ-OPP-2013-0251 Simazine EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(74 pp, 1,108 K, About PDF) Simazine: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(196 pp, 4,504 K, About PDF)
Tebuconazole 107534-96-3 EPA-HQ-OPP-2015-0634 Tebuconazole EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(89 pp, 1,181 K, About PDF) Tebuconazole: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(237 pp, 2,842 K, About PDF)
Triadimefon 43121-43-3 EPA-HQ-OPP-0258 Triadimefon EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(69pp, 1,033 K, About PDF) Triadimefon: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(144 pp, 2,621 K, About PDF)
Trifluralin 1582-09-8 EPA-HQ-OPP-2012-0417 Trifluralin EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(66 pp, 1,071 K, About PDF) Trifluralin: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(304 pp, 4,864 K, About PDF)

Final decisions will be made for these chemicals in regard to the need of Tier 2 tests as detailed in the OIG Report.

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Last updated on July 30, 2024