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Cumulative Impacts Research

In everyday life, people can be exposed to numerous pollutants from a wide array of sources through multiple media and pathways. Chemical stressors in environmental media (air, water, land) and non-chemical stressors (e.g., social determinants of health, extreme weather events) aggregate and accumulate over time from one or more sources in the built, natural, and social environments, affecting individuals and communities in both positive and negative ways―referred to as cumulative impacts. In communities, particularly those already overburdened, disproportionate impacts can arise from unequal environmental conditions and exposure to multiple stressors. Additionally, changes in climate can exacerbate many of these disproportionate impacts.

Following the Science

EPA scientist in lab coat inspects a test tube filled with purple liquid.

EPA’s programs and policies have greatly improved air, water, and soil quality and reduced chemical exposures as measured with national indicators. Scientific evaluations of the distribution of pollution-emitting facilities, adverse environmental exposures, and environmental health impacts show, however, that some places have substantially higher levels of environmental pollution and related adverse health conditions than others.

EPA has proposed that adding a consideration of the cumulative impacts of existing pollution levels and associated health status into its decision-making processes will improve its ability to fulfill its mission to protect human health and the environment. EPA has made cumulative impacts research a priority to bolster the scientific basis for developing approaches for evaluating and improving environmental conditions in America’s communities.

Healthy and Resilient Communities Research Webinar Series

Three children flying a lite running in a field at sunset.

The  Healthy and Resilient Communities Research Webinar Series communicates research and tools intended to help communities and local decision-makers protect their assets and reduce vulnerabilities. Many of these webinars address scientific approaches to cumulative impacts, environmental quality, and environmental health.

How EPA’s Research is Addressing Cumulative Impacts

Related Resources

  • ORD Strategic Research Action Plans
  • FY 2023–FY 2026 EPA Strategic Plan
  • Science Advisory Board (SAB) - The Chartered SAB consulted with EPA on research needed to improve the state of the science supporting cumulative impact assessments as part of public meetings.

Solving longstanding environmental health problems requires an accurate and realistic assessment of the effects from combined exposures to chemical and non-chemical stressors (cumulative impacts) that inform decision-making at all levels.

EPA’s Office of Research and Development (ORD) aims to support federal, tribal, state, and community decision-making by strengthening the scientific foundation for assessing cumulative impacts, exposures, and risks through existing and new methods, tools, data, and monitoring. Cumulative impacts research is a priority to bolster the scientific basis for identifying actions that can improve community health and well-being.

Over the past year, ORD developed fiscal years 2023-2026 Strategic Research Action Plans (StRAPs) for each of its six National Research Programs. The StRAPs integrate efforts to improve our understanding of cumulative impacts to support real-world assessments of both adverse and beneficial health and environmental effects.

Cumulative Impacts Research Report

The front cover of the Cumulative Impacts Research Report.

ORD published the final report, Cumulative Impacts Research: Recommendations for EPA’s Office of Research and Development, to inform the 2023-2026 StRAPs. This report focuses on recommendations to enhance cumulative impact research that are applicable across the National Research Programs and includes recommendations for how ORD can provide management support to facilitate this complex research.

This report represents ORD’s commitment to develop an integrated cumulative impact research portfolio, in collaboration with others, to inform decision-making at all levels.

  • The recommendations in the report are already informing actions within ORD to advance the state of the science, and we are prepared to do more as we implement cumulative impacts research in the years to come.
  • Building on the broad input we received from partners and stakeholders, the report presents recommendations that will assist ORD with integrating research efforts to improve our understanding of cumulative impacts and conduct real-world assessments.
  • Both cumulative impacts and cumulative impact assessment are defined in the interest of providing clarity and consistency across ORD’s research portfolio.
  • Research gaps and barriers to implementing cumulative impact research at EPA are identified and recommendations are made for advancing this research as an explicit part of each of ORD’s six 2023-2026 StRAPs.
  • Recommendations are provided for cumulative impact assessments that will address the unique vulnerabilities of children and vulnerable populations.

This report was prepared by an interdisciplinary group of EPA scientists and experts. It is based on the scientific literature, with input from EPA programs and regions; states, tribes, and community representatives; and the EPA Science Advisory Board (SAB) and public comments collected during SAB consultation. 

Download the report:  Cumulative Impacts: Recommendations for ORD Research (PDF) (5.17 MB)

Research Grant Information

EPA provides grants and funding to the nation's leading researchers to improve the scientific basis for decisions on health and environmental issues. You can sign up to receive email notifications about research grant opportunities and news releases.

Status Name
Closed for Application

Community-Based Research for Effective Programs, Policies, and Decisions to Mitigate Cumulative Health Impacts and Environmental Health Disparities in Underserved Communities Request for Applications (RFA)

Closed for Application

Center for Early Lifestage Vulnerabilities to Environmental Stressors - Cumulative Health Impacts for Children in Underserved Rural Agricultural Communities in the United States Request for Applications (RFA)

Awarded

Cumulative Health Impacts at the Intersection of Climate Change, Environmental Justice, and Vulnerable Populations/Lifestages: Community-Based Research for Solutions

Awarded

Centers for Early Lifestage Vulnerabilities to Environmental Stressors

Awarded

Contaminated Sites, Natural Disasters, Changing Environmental Conditions and Vulnerable Communities: Research to Build Resilience

Closed Grant

Integrating Human Health and Well-Being with Ecosystem Services

Closed Grant

Using a Total Environment Framework (Built, Natural, Social Environments) to Assess Life-Long Health Effects of Chemical Exposure

Search for Cumulative Impact Research Publications

EPA's Science Inventory is a searchable database of research products primarily from EPA's Office of Research and Development. Science Inventory records provide descriptions of the product, contact information, and links to available printed material or websites.

See Cumulative Impacts Research Publications in the Science Inventory

Health Research

  • Children's Environmental Health Research
  • Community Public Health
  • Cumulative Impacts Research
  • Funding, Resources, & Partnerships
  • Health & the Environment
  • Health Impact Assessments
Contact Us About Health Research
Contact Us to ask a question, provide feedback, or report a problem.
Last updated on February 19, 2025
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