EPA Announces Proposed Registration of Pesticide Fluoxapiprolin

Released August 13, 2025

Today, the U.S. Environmental Protection Agency (EPA) released for public comment its proposed registration for one technical and one end-use product containing the new active ingredient fluoxapiprolin, a broad-spectrum fungicide proposed for use on Brassica head and stem vegetables, bulb vegetables, cucurbit vegetables, fruiting vegetables, grapes, leafy vegetables, leaf petiole vegetables and potatoes. Fluoxapiprolin, when used according to label instructions, does not result in risks of concern for human health or the environment.

Fluoxapiprolin provides an alternative active ingredient for control of diseases like downy mildew, late blight or phytophthora blight. This new active ingredient is expected to be a useful addition to Integrated Pest Management programs. It would also give farmers an additional tool to help manage fungal diseases on crops.  

In addition to its proposed registration decision, EPA is releasing human health and ecological risk assessments for the fungicide, as well as a determination that there would be no effects to listed species under the Endangered Species Act. EPA is not requiring any additional data to assess risk to human health or the environment.

After considering public comments on the proposed registration and risk assessments, EPA will determine whether the registration action meets the standard for registration under the Federal Insecticide, Fungicide and Rodenticide Act. If EPA determines that the registration action can be granted, EPA will finalize the decision. 

To read more about the proposed registration of fluoxapiprolin and to comment, see docket EPA-HQ-OPP-2022-0980 at www.regulations.gov. The public comment period will be open for 30 days, closing on Sep 12, 2025.