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  2. Reviewing New Chemicals under the Toxic Substances Control Act (TSCA)

Chemistry Assistance Manual for Premanufacture Notification Submitters under TSCA

The Chemistry Assistance Manual for Premanufacture Notification Submitters is designed to assist persons involved with the design and development of new chemical substances with certain technical aspects of submitting Premanufacture Notices (PMNs) to EPA under the Toxic Substances Control Act. It is hoped that, with this information, submitters will be able to develop more physicochemical property data and other technical information for new substances so that the Agency's ability to perform accurate risk assessments will increase.

  • Chemistry assistance manual for Premanufacture Notification submitters (pdf) (414.13 KB)

Reviewing New Chemicals under the Toxic Substances Control Act (TSCA)

  • Basic Information
  • EPA's Review Process
  • Filing a Premanufacture Notice with EPA
  • Regulatory Actions Under TSCA section 5
  • Premanufacture Notice Status
Reviewing New Chemicals under TSCA Contact Us
Contact Us to ask a question, provide feedback, or report a problem.
Last updated on March 10, 2025
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