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  1. Home
  2. Reviewing New Chemicals under the Toxic Substances Control Act (TSCA)

Program Contacts and Mailing/Courier Information

On this page:
  • Mailing/Courier Information
  • Schedule a Pre-Submission Meeting

Mailing/Courier Information

WARNING - Do not e-mail any Confidential Business Information (CBI) to EPA. EPA's e-mail system is not secured to protect CBI.

General Inquiries and Prenotice Communications

TSCA Hotline

The Toxic Substances Control Act Hotline (tsca-hotline@epa.gov) is available to quickly answer general questions  and document requests about TSCA requirements. The TSCA Hotline operates Monday through Friday, from 8:00 a.m. to 6:00 p.m. Eastern time. Call 1-800-471-7127.

U.S. Mail

U.S. EPA
Office of Pollution Prevention & Toxics
New Chemicals Program (7405M)
1200 Pennsylvania Avenue, NW
Washington, DC 20460

Courier

Use the following direct address to send material by courier. (The building guards will need a New Chemicals Program staff contact phone and room number):

U.S. EPA
Office of Pollution Prevention & Toxics (New Chemicals Program)
EPA East Building, Room 4133
1201 Constitution Avenue, NW
Washington, DC 20004-3302.

Main phone number: 202-564-8469

Fax: 202-564-9490

Schedule a Pre-Submission Meeting

Please DO NOT INCLUDE CONFIDENTIAL BUSINESS INFORMATION in the meeting request.

Please DO NOT INCLUDE CONFIDENTIAL BUSINESS INFORMATION in the meeting request.

Please DO NOT INCLUDE CONFIDENTIAL BUSINESS INFORMATION in the meeting request.

Reviewing New Chemicals under the Toxic Substances Control Act (TSCA)

  • Basic Information
  • EPA's Review Process
  • Filing a Premanufacture Notice with EPA
  • Regulatory Actions Under TSCA section 5
  • Premanufacture Notice Status
Reviewing New Chemicals under TSCA Contact Us
Contact Us to ask a question, provide feedback, or report a problem.
Last updated on May 1, 2025
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