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  2. Safe Drinking Water Act

2021 Human Health Benchmarks for Pesticides

Related Information

  • Health Based Screening Levels (HBSLs) developed by U.S. Geological Survey for contaminants without NPDWRs or HHBPs
  • Human Health Benchmarks

Advanced testing methods now allow for the detection of pesticides in water at very low levels. Small amounts of pesticides detected in drinking water or source water for drinking water do not necessarily indicate a health risk to consumers. EPA has developed human health benchmarks for 430 pesticides to provide information to enable Tribes, states, and water systems to evaluate: (1) whether the detection level of a pesticide in drinking water or sources of drinking water may indicate a potential health risk; and (2) to help to prioritize water monitoring efforts.

The HHBPs Table includes noncancer benchmarks for exposure to pesticides that may be found in surface or ground water sources of drinking water. Noncancer benchmarks for acute (one-day) and chronic (lifetime) drinking water exposures to each pesticide were derived for the most sensitive life stage, based on the available information. The table also includes cancer benchmarks for 48 of the pesticides that have toxicity information that indicates the potential to lead to cancer. The HHBP table includes pesticides for which EPA’s Office of Pesticide Programs has available toxicity data but for which EPA has not yet developed either enforceable National Primary Drinking Water Regulations (i.e., MCLs) or non-enforceable HAs.

Common Name and
Reference Document
CAS Number Acute or One Day PAD (RfD) (mg/kg/day) Acute or a, f One Day HHBPs (ppb) Acute HHBP Sensitive Lifestage/ Population Chronic or Lifetime PAD (rfD) (mg/kg/day) Chronic or b, f Lifetime HHBPs (ppb) Chronic HHBP Sensitive Lifestage/Population Cancer Quantification c (Q1) Values (CSF) (mg/kg/per day) -1 Carcinogenic d, e HHBP (E-6 to E-4 ) (ppb)
1,2,4-Triazole 288-88-0 0.03 200 Children 0.005 30 General Population - -
2, 4 - DB DMA 2758-42-1 0.15 4200 Females 13-49 yrs 0.15 890 General Population - -
2,4-DP-p + salt & ester 15165-67-0 1.25 8330 Children 0.06 400 General Population - -
2,6-Dichlorobenzamide (BAM) 2008-58-4 0.1 700 Children 0.045 270 General Population - -
3,5-Dibromo-4-hydroxybenzonitrile butyrate 3861-41-4 0.08 500 Children 0.015 89 General Population - -
4-Chlorophenoxyacetic acid 122-88-3 -- -- -- 1.32 7810 General Population - -
ADBACg 53516-76-0
68424-85-1
8001-54-5
139-08-2
8045-21-4
73049-75-9
121-54-0
1330-85-4
61789-71-7
85409-23-0
689-56-79-6
68989-01-5
68391-01-5
63449-41-2
61789-18-2
-- -- -- 0.44 2600 General Population - -
Abamectin 71751-41-2 0.0025 17 Children 0.0025 15 General Population - -
Acephate 115096-11-2
30560-19-1
0.0003 2 Children 0.0003 2 Females 13-49 yrs - -
Acequinocyl 57960-19-7 0.073 490 Children 0.027 160 General Population - -
Acetamiprid 135410-20-7 0.1 700 Children 0.071 420 General Population - -
Acetochlor 34256-82-1 -- -- -- 0.02 100 General Population - -
Acibenzolar-S-methyl 135158-54-2 0.082 550 Children 0.082 460 Females 13-49 yrs - -
Afidopyropen 915972-17-7 0.16 4500 Females 13-49 yrs 0.08 500 General Population - -
Allethrinsh 584-79-2 0.03 200 Children 0.008 50 General Population - -
Alpha-Cypermethrin 67375-30-8 0.005 30 Children -- -- -- - -
Aluminum Phosphide 20859-73-8 0.018 120 Children 0.0113 66.9 General Population - -
Amicarbazone 129909-90-6 0.1 700 Children 0.023 140 General Population - -
Aminocyclopyrachlor + ester & salt 858954-83-3 -- -- -- 2.79 16500 General Population - -
Aminopyralid + salts 150114-71-9 -- -- -- 0.5 3000 General Population - -
Amisulbrom 348635-87-0 2 10000 Children 0.54 3200 General Population - -
Amitraz 33089-61-1 0.0125 83.3 Children 0.0005 3 General Population - -
Anthraquinone 84-65-1 -- -- -- -- -- -- 0.0617 0.48-48.0
Aquashade 2650-18-2
92170-50-8
1394-21-0
-- -- -- 5 30000 General Population - -
Asulam + sodium salt 3337-71-1 -- -- -- 0.36 2100 General Population - -
Azinphos-methylg 86-50-0 0.003 20 Children 0.0015 8.9 General Population - -
Azoxystrobin 131860-33-8 0.67 4500 Children 0.18 1070 General Population - -
Benalaxyl-M 98243-83-5 -- -- -- 0.02 100 General Population 0.0059 5.01-501
Benfluralin 1861-40-1 -- -- -- 0.005 30 General Population - -
Benomyl 17804-35-2 0.025 170 Children 0.013 77 General Population 0.00239 12.4-1240
Bensulfuron methyl 83055-99-6 -- -- -- 0.2 1000 General Population - -
Bensulide 741-58-2 0.15 1000 Children 0.005 30 General Population - -
Benthiavalicarb-isopropyl 177406-68-7 -- -- -- 0.099 590 General Population 0.062795 0.47115-47.115
Benzene Sulfonic Acid 68584-22-5 -- -- -- 0.5 3000 General Population - -
Benzobicyclon 156963-66-5 -- -- -- 0.636 3760 General Population - -
Benzobicyclon (Metabolite B) 156963-66-5 0.00027 1.8 Children 0.00004 0.2 General Population - -
Benzovindiflupyr 1072957-71-1 0.1 700 Children 0.082 490 General Population - -
Beta Cyfluthrin 68359-37-5 0.0117 78 Children -- -- -- - -
Bicyclopyrone 3520 I 0-68-5 0.01 300 Females 13-49 yrs 0.00028 1.7 General Population - -
Bifenazate 149877-41-8 0.1 3000 Females 13-49 yrs 0.01 60 General Population - -
Bifenthrin 82657-04-3 0.031 210 Children -- -- -- - -
Bispyribac-sodium 125401-92-5 -- -- -- 0.1 600 General Population - -
Bitertanol 55179-31-2 0.05 1000 Females 13-49 yrs 0.0021 12 General Population - -
Bixafen 581809-46-3 2.5 17000 Children 0.03 200 General Population - -
Boscalid 188425-85-6 -- -- -- 0.22 1300 General Population - -
Bromoxynil, phenol + esters 56634-95-8 0.08 500 Children 0.015 89 General Population 0.103 0.287-28.7
Bromuconazoleh 116255-48-2 0.1 3000 Females 13-49 yrs 0.009 50 General Population - -
Buprofezin 69327-76-0 2 60000 Females 13-49 yrs 0.033 200 General Population - -
Butafenacil 134605-64-4 -- -- -- 0.012 71 General Population - -
Butoxypolypropylene Glycoli 9003-13-8 -- -- -- 1.2 7100 General Population - -
Butralin 33629-47-9 0.082 2300 Females 13-49 yrs 0.1 600 General Population - -
Cacodylic acid + sodium salt 124-65-2 0.12 800 Children 0.014 83 General Population - -
Cadusafos 95465-99-9 0.00002 0.1 Children 0.000001 0.006 General Population - -
Captan 133-06-2 0.1 3000 Females 13-49 yrs 0.13 770 General Population - -
Carbendazim (MBC) 10605-21-7 0.14 930 Children 0.14 830 General Population 0.00239 12.4-1240
Carfentrazone-ethyl 128639-02-1 -- -- -- 0.03 200 General Population - -
Chlorantraniliprole 500008-45-7 -- -- -- 1.58 9350 General Population - -
Chlorethoxyfos 54593-83-8 0.00014 0.93 Children 0.00005 0.3 Females 13-49 yrs - -
Chlorfenapyr 122453-73-0 0.05 300 Children 0.05 300 General Population - -
Chlorflurenol Methyl Ester 2536-31-4 -- -- -- 0.1 600 General Population - -
Chlorimuron-ethyl 90982-32-4 1 7000 Children 0.09 500 General Population - -
Chlormequat chloride 999-81-5 1 7000 Children 0.05 300 General Population - -
Chloronebg 2675-77-6 -- -- -- 0.013 77 General Population - -
Chlorpropham 101-21-3 -- -- -- 0.005 30 General Population - -
Chlorpyrifos-methyl 5598-13-0 0.00033 2.2 Children 0.00033 1.9 Females 13-49 yrs - -
Chlorsulfuron 64902-72-3 -- -- -- 0.05 300 General Population - -
Clethodim 99129-21-2 1 7000 Children 0.3 2000 General Population - -
Clodinafop-propargyl 105512-06-9 0.05 1000 Females 13-49 yrs 0.0032 19 General Population - -
Clofentezine 74115-24-5 -- -- -- 0.013 77 General Population 0.0376 0.787-78.7
Clomazone 81777-89-1 1 30000 Females 13-49 yrs 0.84 5000 General Population - -
Clopyralid + salts 57754-85-5 -- -- -- 0.15 890 General Population - -
Cloquintocet-mexyl 99607-70-2 1 30000 Females 13-49 yrs 0.04 200 General Population - -
Cloransulam-Methyl 147150-35-4 -- -- -- 0.1 600 General Population - -
Clothianidin 210880-92-5 0.25 1700 Children 0.098 580 General Population - -
Coumaphos 56-72-4 0.0025 17 Children 0.0003 2 General Population - -
Cyantraniliprole 736994-63-1 -- -- -- 0.01 60 General Population - -
Cyazofamid 120116-88-3 -- -- -- 0.948 5610 General Population - -
Cyclanilide 113136-77-9 0.5 3000 Children 0.002 10 General Population - -
Cycloate 1134-23-2 0.066 440 Children 0.005 30 General Population - -
Cyflufenamid 180409-60-3 -- -- -- 0.044 260 General Population - -
Cyflumetofen 400882-07-7 -- -- -- 0.17 1000 General Population - -
Cyfluthrin 68359-37-5 0.0117 78 Children -- -- -- - -
Cyhalofop-butyl 122008-85-9 -- -- -- 0.01 60 General Population - -
Cyhalothrin 68085-85-8 0.00093 6.2 Children -- -- -- - -
Cyhexatin 13121-70-5 0.0067 45 Children 0.0025 15 General Population - -
Cymoxanil 57966-95-7 0.08 2000 Females 13-49 yrs 0.03 200 General Population - -
Cypermethrin 52315-07-08 0.0716 477 Children -- -- -- - -
Cyproconazole 94361-06-5 0.02 600 Females 13-49 yrs 0.01 60 General Population - -
Cyprodinil 121552-61-2 2 10000 Children 0.027 160 General Population - -
Cyprosulfamide 221667-31-8 -- -- -- 0.39 2300 General Population - -
Cyromazine 66215-27-8 0.83 5500 Children 0.5 3000 General Population - -
DDAC 7173-51-5 0.1 3000 Females 13-49 yrs 0.1 600 General Population - -
DDBSA 27176-87-0 -- -- -- 0.5 3000 General Population - -
Daminozide 1596-84-5 -- -- -- -- -- -- 0.0087 3.4-340
Dantochlor (BCDMH) 118-52-5 1 30000 Females 13-49 yrs 1 6000 Females 13-49 yrs - -
Deltamethrin 52918-63-5 0.015 100 Children -- -- -- - -
Desmedipham 13684-56-5 0.1 700 Children 0.04 200 General Population - -
Diaminochlorotriazine (DACT) 3397-62-4 0.01 300 Females 13-49 yrs 0.0018 11 General Population - -
Dichlobenil 1194-65-6 0.45 13000 Females 13-49 yrs 0.01 60 General Population - -
Dichloran 99-30-9 0.05 1000 Females 13-49 yrs 0.0025 15 General Population - -
Dichlormid 37764-25-3 0.01 70 Children 0.0022 13 General Population - -
Dichlorvos 62-73-7 0.00083 5.5 Children 0.00006 0.3 Females 13-49 yrs - -
Diclofop-methyl 51338-27-3 0.1 3000 Females 13-49 yrs 0.0023 14 General Population 0.0736 0.402-40.2
Diclosulam 145701-21-9 -- -- -- 0.05 300 General Population - -
Dicofolg 115-32-2 0.05 300 Children 0.0004 2 General Population - -
Dicrotophos 141-66-2 0.00007 0.5 Children 0.00003 0.2 Females 13-49 yrs - -
Diethanolamine Mefluidide 53780-36-2 0.58 3900 Children 0.015 89 General Population - -
Diethofencarb 87130-20-9 -- -- -- 0.5 3000 General Population - -
Difenoconazole 119446-68-3 0.25 1700 Children 0.01 60 General Population - -
Difenzoquat methyl sulfate 43222-48-6 -- -- -- 0.083 490 General Population - -
Diflubenzuron 35367-38-5 -- -- -- 0.02 100 General Population - -
Diflufenzopyr + sodium salt 109293-97-2 1 30000 Females 13-49 yrs 0.26 1500 General Population - -
Dimethenamid 87674-68-8 2 10000 Children 0.05 300 General Population - -
Dimethenamid-P 163515-14-8 2 10000 Children 0.05 300 General Population - -
Dimethipin 55290-64-7 -- -- -- 0.0218 129 General Population - -
Dimethoate 60-51-5 0.013 87 Children 0.0022 13 General Population - -
Dimethomorph 110488-70-5 0.25 1700 Children 0.11 650 General Population - -
Dinocap 39300-45-3 0.004 100 Females 13-49 yrs 0.00038 2.2 General Population - -
Dinotefuran 165252-70-0 1.25 8330 Children 1 6000 General Population - -
Diphacinoneg 82-66-6 0.002 10 Children -- -- -- - -
Diphenylamine 122-39-4 -- -- -- 0.1 600 General Population - -
Diquat dibromide 85-00-7 0.75 5000 Children 0.005 30 General Population - -
Disodium methanearsonate 144-21-8 0.1 700 Children 0.03 200 General Population - -
Dithianon 3347-22-6 0.02 600 Females 13-49 yrs 0.006 40 General Population - -
Dithiopyr 97886-45-8 -- -- -- 0.0036 21 General Population - -
Dodine 2439-10-3 -- -- -- 0.02 100 General Population - -
EPTC (Ethyl dipropylthiocarbamate) 759-94-4 0.2 1000 Children 0.05 300 General Population - -
Ecolyst 274671-61-3 0.5 3000 Children 0.14 830 General Population - -
Emamectin Benzoate 137512-74-4 0.0025 17 Children 0.0025 15 General Population - -
Endosulfan 115-29-7 0.015 100 Children 0.006 40 General Population - -
Epoxiconazole 133855-98-8 0.05 1000 Females 13-49 yrs 0.02 100 General Population 0.0304 0.973-97.3
Esfenvalerate 66230-04-4 0.011 73 Children -- -- -- - -
Ethaboxam 162650-77-3 -- -- -- 0.055 330 General Population - -
Ethalfluralin 55283-68-6 0.75 21000 Females 13-49 yrs 0.04 200 General Population 0.089 0.33-33
Ethametsulfuron 97780-06-8 -- -- -- 4.5 27000 General Population - -
Ethephon 16672-87-0 0.06 400 Children 0.06 400 General Population - -
Ethiprole 181587-01-9 0.35 2300 Children 0.03 200 General Population - -
Ethofumesate 26225-79-6 0.3 8000 Females 13-49 yrs 0.3 2000 Females 13-49 yrs - -
Ethoprop 13194-48-4 0.00042 2.8 Children 0.000065 0.37 Females 13-49 yrs 0.0281 1.05-105
Ethoxyquin 91-53-2 1 7000 Children 0.04 200 General Population - -
Ethyl Parathiong 56-38-2 0.0003 2 Children 0.00003 0.2 General Population - -
Ethylene Chlorohydring 107-07-3 0.1 700 Children 0.045 270 General Population - -
Etofenprox 80844-07-1 -- -- -- 0.0255 151 General Population - -
Etoxazole 153233-91-1 -- -- -- 0.046 270 General Population - -
Etridiazole (Terrazole) 2593-15-9 -- -- -- 0.06 400 General Population 0.0358 0.826-82.6
Famoxadone 131807-57-3 -- -- -- 0.0014 8.3 General Population - -
Fenamidone 161326-34-7 1.25 8330 Children 0.0283 167 General Population - -
Fenarimol 60168-88-9 -- -- -- 0.006 40 General Population - -
Fenazaquin 120928-09-8 0.15 1000 Children 0.05 300 General Population - -
Fenbuconazole 114369-43-6 0.3 8000 Females 13-49 yrs 0.03 200 General Population 0.00359 8.24-824
Fenbutatin-oxide 13356-08-6 0.2 1000 Children 0.05 300 General Population - -
Fenhexamid 126833-17-8 -- -- -- 0.17 1000 General Population - -
Fenitrothion 122-14-5 0.00025 1.7 Children 0.00013 0.77 General Population - -
Fenoxaprop-ethyl 66441-23-4 0.32 9000 Females 13-49 yrs 0.0025 15 General Population - -
Fenpicoxamid (XDE-777) 517875-34-2 -- -- -- 0.4 2000 General Population - -
Fenpropathrin 39515-41-8 0.05 300 Children -- -- -- - -
Fenpropidin 67306-00-7 0.07 500 Children 0.023 140 General Population - -
Fenpropimorph 67564-91-4 0.15 4200 Females 13-49 yrs 0.032 190 General Population - -
Fenpyrazamine 473798-59-3 0.8 5000 Children 0.3 2000 General Population - -
Fenpyroximate 134098-61-6 0.375 2500 Children 0.01 60 General Population - -
Fenthiong 55-38-9 0.0007 5 Children 0.00007 0.4 General Population - -
Ferbam 14484-64-1 0.014 93 Children 0.015 89 General Population - -
Fipronil 120068-37-3 0.025 170 Children 0.0002 1 General Population - -
Flazasulfuron 104040-78-0 0.5 3000 Children 0.013 77 General Population - -
Flonicamid 158062-67-0 -- -- -- 0.04 200 General Population - -
Florasulam 145701-23-1 -- -- -- 0.05 300 General Population - -
Fluazifop 69806-50-4 0.5 10000 Females 13-49 yrs 0.0074 44 General Population - -
Fluazifop-P-Butyl 79241-46-6 0.5 3000 Children 0.0051 30 General Population - -
Fluazinam 79622-59-6 0.07 2000 Females 13-49 yrs 0.011 65 General Population - -
Flubendiamide 272451-65-7 0.995 6630 Children 0.024 140 General Population - -
Flucarbazone-sodium 181274-17-9 -- -- -- 0.074 440 General Population - -
Fludioxonil 131341-86-1 -- -- -- 0.33 2000 General Population - -
Fluensulfone 318290-98-1 0.16 1100 Children 0.1 600 General Population - -
Flufenacet (Thiaflumide) 142459-58-3 0.0017 11 Children 0.0017 10 General Population - -
Flufenoxuron 101463-69-8 -- -- -- 0.0375 222 General Population - -
Flufenpyr-ethyl 188489-07-8 -- -- -- 0.4 2000 General Population - -
Flumetralin 62924-70-3 0.5 10000 Females 13-49 yrs -- -- -- - -
Flumetsulam (XRD-498) 98967-40-9 -- -- -- 1 6000 General Population - -
Flumiclorac pentyl 87546-18-7 -- -- -- 1 6000 General Population - -
Flumioxazin 103361-09-7
141490-50-8
0.03 800 Females 13-49 yrs 0.02 100 General Population - -
Fluopicolide 239110-15-7 -- -- -- 0.2 1000 General Population - -
Fluopyram 658066-35-4 0.5 3000 Children 0.012 71 General Population - -
Fluoxastrobin 361377-29-9 -- -- -- 0.015 89 General Population - -
Flupyradifurone 951659-40-8 0.35 2300 Children 0.078 460 General Population - -
Fluridone 59756-60-4 1.25 8330 Children 0.15 890 General Population - -
Fluroxypyr + acid 81406-37-3
69377-81-7
-- -- -- 1 6000 General Population - -
Flurprimidol 56425-91-3 0.1 3000 Females 13-49 yrs 0.04 200 General Population - -
Flusilazole 85509-19-9 0.02 600 Females 13-49 yrs 0.002 10 General Population - -
Fluthiacet methyl 117337-19-6 -- -- -- 0.001 6 General Population 0.207 0.143-14.3
Flutolanil 66332-96-5 -- -- -- 0.5 3000 General Population - -
Flutriafol 76674-21-0 0.075 2100 Females 13-49 yrs 0.05 300 General Population - -
Fluxapyroxad 907204-31-3 1.25 8330 Children 0.021 120 General Population - -
Folpet 133-07-3 0.1 3000 Females 13-49 yrs 0.09 500 General Population - -
Fomesafen + sodium 72178-02-0 1 7000 Children 0.01 60 General Population - -
Forchlorfenuron 68157-60-8 -- -- -- 0.07 400 General Population - -
Formetanate hydrochloride 23422-53-9 0.00032 2.1 Children -- -- -- - -
Fosetyl-Al 39148-24-8 -- -- -- 2.5 15000 General Population - -
Fosthiazate 98886-44-3 0.0065 43 Children 0.00096 5.7 General Population - -
Furfural 98-01-1 0.8 5000 Children 0.1 600 General Population 0.0349 0.848-84.8
Furfuryl Alcohol 98-00-00 -- -- -- -- -- -- 0.131 0.226-22.6
Furilazole 121776-33-8 0.1 3000 Females 13-49 yrs 0.0009 5 General Population 0.0274 1.08-108
Gamma Cyhalothrin 76703-62-3 0.00093 6.2 Children -- -- -- - -
Gardona 22248-79-9 0.0028 19 Children 0.0028 16 Females 13-49 yrs 0.00183 16.2-1620
Glufosinate-ammonium 77182-82-2 0.063 1800 Females 13-49 yrs 0.006 40 General Population - -
Halauxifen-methyl 943831-98-9 -- -- -- 0.03 200 General Population - -
Halosulfuron methyl (MON 1200) 100784-20-1 0.5 10000 Females 13-49 yrs 0.1 600 General Population - -
Hexaconazoleg 79983-71-4 0.0025 71 Females 13-49 yrs 0.02 100 General Population 0.016 1.8-180
Hexythiazox 78587-05-0 -- -- -- 0.025 150 General Population - -
Hydramethylnon 67485-29-4 -- -- -- 0.017 100 General Population - -
Hydrogen cyanamide (Cyanamide) 420-04-2 0.005 30 Children 0.002 10 General Population 0.0664 0.446-44.6
Hydrogen cyanide 74-90-8 0.004 30 Children -- -- -- - -
Hydroxyatrazine 2163-68-0 -- -- -- 0.0676 400 General Population - -
Hymexazol 10004-44-1 1.5 10000 Children 0.3 2000 General Population - -
Imazalil + sulfate 35554-44-0 0.1 3000 Females 13-49 yrs 0.108 639 General Population 0.0611 0.484-48.4
Imazamethabenz-methyl 81405-85-8 5 100000 Females 13-49 yrs 0.25 1500 General Population - -
Imazapici 104098-48-8 -- -- -- 0.137 811 General Population - -
Imazapyr 81334-34-1 -- -- -- 2.5 15000 General Population - -
Imazaquin + salts 35554-44-0 -- -- -- 0.25 1500 General Population - -
Imazethapyri 81335-77-5 -- -- -- 2.5 15000 General Population - -
Imazosulfuron 122548-33-8 4 30000 Children 0.75 4400 General Population - -
Imidacloprid 138261-41-3 0.08 500 Children 0.08 500 General Population - -
Indaziflam 950782-86-2 0.075 500 Children 0.02 100 General Population - -
Indoxacarb 173584-44-6 0.12 800 Children 0.02 100 General Population - -
Inpyrfluxam 1352994-67-2 0.3 2000 Children 0.26 1500 General Population - -
Iodosulfuran Methyl-Sodium 144550-36-7 1 7000 Children 0.073 430 General Population - -
Ipoconazole 125225-28-7 0.1 3000 Females 13-49 yrs 0.015 89 General Population - -
Iprodione 36734-19-7 -- -- -- 0.061 360 General Population 0.0439 0.674-67.4
Iprovalicarb 140923-17-7 -- -- -- 0.0262 155 General Population 0.000447 66.2-6620
Isofenphosg 25311-71-1 0.0007 5 Children 0.00008 0.5 General Population - -
Isofetamid 875915-78-9 -- -- -- 0.77 4600 General Population - -
Isopyrazam 881685-58-1 0.3 2000 Children 0.055 330 General Population 0.00629 4.70-470
Isotianil 224049-04-1 -- -- -- 0.27 1600 General Population - -
Isoxaben 82558-50-7 -- -- -- 0.05 300 General Population - -
Isoxadifen-ethyl 163520-33-0 0.15 4200 Females 13-49 yrs 0.033 200 General Population - -
Isoxaflutole 141112-29-0 0.02 600 Females 13-49 yrs 0.02 100 General Population 0.0114 2.60-260
Kasugamycin 6980-18-3 -- -- -- 0.11 650 General Population - -
Kathon 930 64359-81-5 0.03 200 Children 0.002 10 General Population - -
Kresoxim-methyl 143390-89-0 -- -- -- 0.36 2100 General Population 0.0029 10-1000
Lactofen 77501-63-4 0.017 480 Females 13-49 yrs 0.008 50 General Population - -
Lambda cyhalothrin 91465-08-6 0.00093 6.2 Children -- -- -- - -
Linuron 330-55-2 0.2 1000 Children 0.0077 46 General Population - -
MCPB Acid 94-81-5 0.142 947 Children 0.044 260 General Population - -
MCPB Sodium Salt 6062-26-6 0.142 947 Children 0.044 260 General Population - -
MCPP-p acid + salts 16484-77-8 1.75 11700 Children 0.04 200 General Population - -
MGK 264 113-48-4 1 30000 Females 13-49 yrs 0.061 360 General Population - -
MSMA-calcium salt 5902-95-4 0.1 700 Children 0.03 200 General Population - -
Mancozeb 8018-01-7 0.5 3000 Children 0.016 90 Females 13-49 yrs 0.0601j 0.492-49.2
Mandestrobin 173662-97-0 -- -- -- 0.92 5400 General Population - -
Mandipropamid 374726-62-2 -- -- -- 0.05 300 General Population - -
Manebg 12427-38-2 0.02 600 Females 13-49 yrs 0.05 300 General Population 0.0601 0.492-49.2
Mefenoxam 70630-17-0 0.5 3000 Children -- -- -- - -
Mefenpyr-diethyl (HOE 107892) 135590-91-9 -- -- -- 0.51 3000 General Population - -
Mefentrifluconazole 1417782-03-6 0.73 21000 Females 13-49 yrs 0.035 210 General Population - -
Mefluidide 53780-34-0 0.58 3900 Children 0.015 89 General Population - -
Mepiquat Chloride 24307-26-4 0.3 2000 Children 0.3 2000 General Population - -
Meptyldinocap (DE-126/Dinocap II) 131-72-6 -- -- -- 0.005 30 General Population - -
Mesosulfuron methyl 208465-21-8 -- -- -- 1.55 9170 General Population - -
Mesotrione 104206-82-8 -- -- -- 0.71 4200 General Population - -
Metaflumizone 139968-49-3 0.33 9300 Females 13-49 yrs 0.04 200 General Population - -
Metalaxyl 57837-19-1 0.5 3000 Children -- -- -- - -
Metaldehyde 9002-91-9 0.3 2000 Children 0.1 600 General Population - -
Metconazole 125116-23-6 0.3 8000 Females 13-49 yrs 0.04 200 General Population - -
Methamidophosg 10265-92-6 0.001 7 Children 0.0001 0.6 General Population - -
Methidathiong 950-37-8 0.002 10 Children 0.0015 8.9 General Population - -
Methiozolin 403640-27-7 -- -- -- 0.43 2500 General Population - -
Methoxyfenozide 161050-58-4 -- -- -- 0.1 600 General Population - -
Methyl bromide 74-83-9 0.14 4000 Females 13-49 yrs 0.022 130 General Population - -
Metiram 9006-42-2 0.01 300 Females 13-49 yrs 0.0004 2 General Population 0.0601 0.492-49.2
Metrafenone 220899-03-6 -- -- -- 0.249 1470 General Population - -
Metsulfuron methyl 74223-64-6 -- -- -- 0.25 1500 General Population - -
Mevinphosg 7786-34-7 0.0003 2 Children 0.000025 0.15 General Population - -
Monosodium acid methanearsonate (MMA) 2163-80-6 0.1 700 Children 0.03 200 General Population - -
Myclobutanil 88671-89-0 0.6 20000 Females 13-49 yrs 0.025 150 General Population - -
Naled 300-76-5 0.0032 21 Children 0.0006 3 Females 13-49 yrs - -
Napropamide 15299-99-7 -- -- -- 0.12 710 General Population - -
Napthalene Acetates 86-86-2
86-87-3
15165-79-4
25545-89-5
2122-70-5
61-31-4
-- -- -- 0.25 1500 General Population - -
Nicosulfuron 111991-09-4 -- -- -- 1.25 7400 General Population - -
Nitrapyrin 1929-82-4 0.16 1100 Children 0.03 200 General Population - -
Norflurazon 27314-13-2 -- -- -- 0.0015 8.9 General Population - -
Novaluron 116714-46-6 -- -- -- 0.011 65 General Population - -
Orthosulfamuron 213464-77-8 -- -- -- 0.05 300 General Population - -
Oryzalin 19044-88-3 0.25 7100 Females 13-49 yrs 0.19 1100 General Population 0.00779 3.80-380
Oxadiazon 19666-30-9 0.12 3400 Females 13-49 yrs 0.005 30 General Population 0.0711 0.416-41.6
Oxydemeton-methylg 301-12-2 0.008 50 Children 0.0001 0.6 General Population - -
Oxyfluorfen 42874-03-3 -- -- -- 0.04 200 General Population 0.0732 0.404-40.4
Oxytetracycline 79-57-2 -- -- -- 0.1 600 General Population - -
Oxytetracycline calcium 7179-50-2 -- -- -- 0.1 600 General Population - -
Oxytetracycline hydrochloride 79-57-2 -- -- -- 0.1 600 General Population - -
PCNB, Pentachloronitrobenzene (Quintozene) 82-68-8 -- -- -- 0.001 6 General Population - -
PHMB 32289-58-0 0.2 6000 Females 13-49 yrs 0.2 1000 General Population - -
Paclobutrazol 76738-62-0 0.3 2000 Children 0.11 650 General Population - -
Paraquat dichloride 1910-42-5 0.05 300 Children 0.005 30 General Population - -
Pebulate 1114-71-2 0.05 300 Children 0.0007 4 Females 13-49 yrs - -
Pendimethalin 40487-42-1 1 7000 Children 0.3 2000 General Population - -
Penflufen 494793-67-8 0.5 3000 Children 0.38 2200 General Population - -
Penoxsulam 219714-96-2 -- -- -- 0.147 870 General Population - -
Penthiopyrad 183675-82-3 1.25 8330 Children 0.27 1600 General Population - -
Permethrin 52645-53-1 0.44 2900 Children -- -- -- - -
Pethoxamid 106700-29-2 -- -- -- 0.17 1000 General Population - -
Phenmedipham 13684-63-4 -- -- -- 0.24 1400 General Population - -
Phorate 298-02-2 0.00083 5.5 Children 0.00017 1 General Population - -
Phosaloneg 2310-17-0 0.03 200 Children 0.002 10 General Population - -
Phosmet 732-11-6 0.0014 9.3 Children 0.00016 0.9 Females 13-49 yrs - -
Phostebupirim (Tebupirimphos) 96182-53-5 0.000158 1.05 Children 0.000041 0.23 Females 13-49 yrs - -
Picoxystrobin 117428-22-5 0.2 1000 Children 0.046 270 General Population - -
Pinoxaden 243973-20-8 0.3 8000 Females 13-49 yrs 0.3 2000 General Population - -
Piperonyl butoxide 51-03-6 5 30000 Children 0.16 950 General Population - -
Pirimiphos-methyl 29232-93-7 0.006 40 Children 0.00073 4.1 Females 13-49 yrs - -
Potassium Mefluidide 83601-83-6 0.58 3900 Children 0.015 89 General Population - -
Prallethrin 23031-36-9 0.025 170 Children -- -- -- - -
Primisulfuron-methyl 86209-51-0 -- -- -- 0.25 1500 General Population - -
Procymidone 32809-16-8 0.035 990 Females 13-49 yrs -- -- -- 0.01339 2.210-221
Prodiamine 29091-21-2 -- -- -- 0.14 830 General Population - -
Profenofos 41198-08-7 0.00199 13.3 Children 0.00012 0.68 Females 13-49 yrs - -
Prohexadione calcium 127277-53-6 -- -- -- 0.2 1000 General Population - -
Prometryn 7287-19-6 -- -- -- 0.04 200 General Population - -
Pronamide (Propyzamide) 23950-58-5 0.04 300 Children 0.013 77 General Population - -
Propamocarb hydrochloride 25606-41-1 2 10000 Children 0.12 710 General Population - -
Propanil 709-98-8 -- -- -- 0.03 200 General Population - -
Propargite 2312-35-8 -- -- -- 0.04 200 General Population 0.192 0.154-15.4
Propetamphos 31218-83-4 0.0005 3 Children 0.0005 3 General Population - -
Propiconazole 60207-90-1 0.3 2000 Children 0.1 600 General Population - -
Propoxur 114-26-1 0.00038 2.5 Children -- -- -- 0.00352 8.41-841
Propoxycarbazone sodium 181274-15-7 -- -- -- 0.748 4430 General Population - -
Propylene oxide 75-56-9 0.21 5900 Females 13-49 yrs 0.001 6 General Population 0.15 0.20-20
Proquinazid 189278-12-4 0.05 300 Children 0.004 20 General Population - -
Prosulfuron 94125-34-5 0.1 700 Children 0.053 310 General Population - -
Prothioconazole 178928-70-6 0.02 600 Females 13-49 yrs 0.01 60 General Population - -
Pydiflumetofen 1228284-64-7 1 7000 Children 0.092 540 General Population - -
Pymetrozine 123312-89-0 0.008 50 Children 0.008 50 General Population 0.0119 2.49-249
Pyraclostrobin 175013-18-0 0.05 1000 Females 13-49 yrs 0.034 200 General Population - -
Pyraflufen ethyl 129630-19-9 -- -- -- 0.2 1000 General Population 0.0332 0.891-89.1
Pyrasulfotole 365400-11-9 0.038 250 Children 0.01 60 General Population - -
Pyrazon 1698-60-8 -- -- -- 0.18 1100 General Population - -
Pyrethrins 8003-34-7 0.07 500 Children 0.004 20 General Population - -
Pyridaben 96489-71-3 0.44 2900 Children 0.022 130 General Population - -
Pyridalyl 179101-81-6 -- -- -- 0.034 200 General Population - -
Pyridate 55512-33-9 0.2 1000 Children 0.11 650 General Population - -
Pyrifluquinazon 337458-27-2 0.05 1000 Females 13-49 yrs 0.06 400 General Population - -
Pyrimethanil 53112-28-0 1 7000 Children 0.17 1000 General Population - -
Pyriofenone 688046-61-9 -- -- -- 0.091 540 General Population - -
Pyriproxyfen 95737-68-1 -- -- -- 0.35 2100 General Population - -
Pyrithiobac-sodium 123343-16-8 -- -- -- 0.587 3470 General Population 0.00105 28.2-2820
Pyroxasulfone 447399-55-5 1 7000 Children 0.02 100 General Population - -
Pyroxsulam 422556-08-9 -- -- -- 1 6000 General Population - -
Quinchlorac 84087-01-4 2 60000 Females 13-49 yrs 0.38 2200 General Population - -
Quinoxyfen 124495-18-7 -- -- -- 0.2 1000 General Population - -
Quizalofop-ethyl 100646-51-3 -- -- -- 0.009 50 General Population - -
Resmethring 10453-86-8 -- -- -- 0.035 210 General Population 0.05621 0.5263-52.63
Rimsulfuron 122931-48-0 -- -- -- 0.118 698 General Population - -
RoteNone 83-79-4 0.015 420 Females 13-49 yrs 0.0004 2 General Population - -
Saflufenacil (BAS 800 H) 372137-35-4 5 30000 Children 0.046 270 General Population - -
Sedaxane 874967-67-6 0.3 2000 Children 0.11 650 General Population - -
Sethoxydim 74051-80-2 1.8 12000 Children 0.14 830 General Population - -
Siduron 1982-49-6 -- -- -- 0.15 890 General Population - -
Sodium Chlorate 7775-09-9 -- -- -- 0.03 200 General Population - -
Sodium Dodecylbenzene Sulfonate 25155-30-0 -- -- -- 0.5 3000 General Population - -
Sodium bentazon 50723-80-3 0.5 3000 Children 0.15 890 General Population - -
Sodium cyanide 143-33-9 0.004 30 Children -- -- -- - -
Spinetoram 187166-40-1
187166-15-0
-- -- -- 0.0249 147 General Population - -
Spinosad 131929-60-7 -- -- -- 0.0249 147 General Population - -
Spirodiclofen 148477-71-8 -- -- -- 0.014 83 General Population 0.0149 1.99-199
Spiromesifen 283594-90-1 -- -- -- 0.0038 22 General Population - -
Spirotetramat 203313-25-1 1 7000 Children 0.05 300 General Population - -
Spiroxamine 118134-30-8 0.1 700 Children 0.025 150 General Population - -
Streptomycin 57-92-1 -- -- -- 0.05 300 General Population - -
Streptomycin Sesquisulfate 3810-74-0 -- -- -- 0.05 300 General Population - -
Sulfentrazone 122836-35-5 0.14 4000 Females 13-49 yrs 0.14 830 General Population - -
Sulfometuron Methyl 74222-97-2 -- -- -- 0.275 1630 General Population - -
Sulfosate (Glyphosate-trimesium)g 81591-81-3 0.33 2200 Children 0.083 490 General Population - -
Sulfosulfuron 141776-32-1 -- -- -- 0.24 1400 General Population - -
Sulfoxaflor 946578-00-3 0.25 1700 Children 0.05 300 General Population - -
Sulfuryl fluoride 2699-79-8 -- -- -- 0.08 500 General Population - -
TCMTB (Busan 72) 21564-17-0 0.25 1700 Children 0.01 60 General Population - -
Tau-fluvalinate 102851-06-9 0.01 70 Children -- -- -- - -
Tebuconazole 107534-96-3 0.029 190 Children 0.029 170 General Population - -
Tebufenozide 112410-23-8 -- -- -- 0.02 100 General Population - -
Teflubenzuron 83121-18-0 -- -- -- 0.021 120 General Population - -
Tefluthrin 79538-32-2 0.005 30 Children -- -- -- - -
Tembotrione 335104-84-2 0.0008 5 Children 0.0004 2 General Population - -
Tepraloxydim 149979-41-9 0.5 3000 Children 0.05 300 General Population - -
Tetrachlorvinphos 961-11-5 0.0028 19 Children 0.0028 16 Females 13-49 yrs 0.00183 16.2-1620
Tetraconazole 112281-77-3 0.5 3000 Children 0.0073 43 General Population - -
Thiabendazole + salt 148-79-8 0.5 3000 Children 0.1 600 General Population - -
Thiacloprid 111988-49-9 0.01 70 Children 0.004 20 General Population 0.0406 0.729-72.9
Thiamethoxam 153719-23-4 0.35 2300 Children 0.012 71 General Population - -
Thidiazuron 51707-55-2 -- -- -- 0.0393 233 General Population - -
Thiencarbazone-methyl 317815-83-1 -- -- -- 1.17 6920 General Population - -
Thifensulfuron methyl 79277-27-3 1.59 44900 Females 13-49 yrs 0.043 250 General Population - -
Thiobencarb 28249-77-6 1 7000 Children 0.01 60 General Population - -
Thiodicarb 59669-26-0 0.0015 10 Children -- -- -- - -
Thiophanate-methyl 23564-05-8 0.4 3000 Children 0.16 950 General Population 0.0116 2.55-255
Thiram 137-26-8 0.014 400 Females 13-49 yrs 0.015 89 General Population - -
Tiafenacil 1220411-29-9 -- -- -- 0.01 60 General Population - -
Tioxazafen 330459-31-9 0.25 1700 Children 0.05 300 General Population - -
Tolfenpyrad 129558-76-5 0.1 700 Children 0.006 40 General Population - -
Tolpyralate 1101132-67-5 0.05 1000 Females 13-49 yrs 0.0093 55 General Population - -
Tolyfluanid 731-27-1 0.17 1100 Children 0.026 150 General Population 0.00159 18.6-1860
Topramezone 210631-68-8 0.008 50 Children 0.004 20 General Population - -
Tralkoxydim 87820-88-0 0.3 8000 Females 13-49 yrs 0.005 30 General Population - -
Triadimefon 43121-43-3 0.034 230 Children 0.034 200 General Population - -
Triadimenol 55219-65-3 0.0034 23 Children 0.0034 20 General Population - -
Triallate 2303-17-5 0.6 4000 Children 0.025 150 General Population 0.0717 0.413-41.3
Triasulfuron 82097-50-5 -- -- -- 0.01 60 General Population - -
Triazole Acetic Acid 28711-29-7 0.1 3000 Females 13-49 yrs 0.09 500 General Population - -
Triazole alanine 114419-45-3 0.1 3000 Females 13-49 yrs 0.09 500 General Population - -
Tribenuron methyl 101200-48-0 3 20000 Children 0.008 50 General Population - -
Tribufos 78-48-8 0.001 7 Children 0.0002 1 Females 13-49 yrs - -
Trichlorfon 52-68-6 0.00007 0.5 Children 0.00007 0.4 Females 13-49 yrs - -
Triclopyr 55335-06-3 0.05 1000 Females 13-49 yrs 0.05 300 General Population - -
Triclosan 3380-34-5 0.3 2000 Children 0.3 2000 General Population - -
Tricyclazole 41814-78-2 0.07 500 Children 0.067 400 General Population - -
Tridemorph 24602-86-6 0.02 600 Females 13-49 yrs 0.01 60 General Population - -
Trifloxystrobin 141517-21-7 2.5 71000 Females 13-49 yrs 0.038 220 General Population - -
Trifloxysulfuron Sodium 290332-10-4 0.5 10000 Females 13-49 yrs 0.237 1400 General Population - -
Triflumezopyrim 1263133-33-0 1 7000 Children 0.17 1000 General Population - -
Triflumizole 68694-11-1 0.25 1700 Children 0.0117 69.2 General Population - -
Triflusulfuron-methyl 126535-15-7 -- -- -- 0.0244 144 General Population - -
Triforine 37273-84-0 -- -- -- 0.22 1300 General Population - -
Trinexapac-Ethyl 95266-40-3 0.6 20000 Females 13-49 yrs 0.32 1900 General Population - -
Triphenyltin hydroxide (TPTH) 76-87-9 0.005 30 Children 0.001 6 General Population 1.83 0.0162-1.62
Triticonazole 131983-72-7 0.5 10000 Females 13-49 yrs 0.17 1000 General Population - -
Uniconazole-P 83657-17-4 0.05 1000 Females 13-49 yrs 0.02 100 General Population - -
Valifenalate 283159-90-0 -- -- -- 0.22 1300 General Population - -
Vinclozolin 50471-44-8 0.006 200 Females 13-49 yrs 0.0012 7.1 General Population - -
Zeta-Cypermethrin 52315-07-08 0.0716 477 Children -- -- -- - -
Zinc Phosphideg 1314-84-7 0.002 10 Children 0.00001 0.06 General Population - -
Ziram 137-30-4 0.05 300 Children 0.016 95 General Population - -
Zoxamidei 156052-68-5 -- -- -- 0.48 2800 General Population - -
d-Phenothrin (Sumithrin) 26002-80-2 0.3 8000 Females 13-49 yrs 0.07 400 General Population - -

Footnotes:

a Formula for deriving Acute HHBP for Children = [aPAD (mg/kg/day) x 1000 (µg/mg)] / [0.15 (L/kg-day) Drinking Water Intake-Body Weight (DWI-BW) ratio]; Formula for deriving Acute HHBP for Females 13-49 Years = [aPAD (mg/kg/day) x 1000 (µg/mg)] / 0.0354 (L/kg/day) DWI-BW ratio

b Formula for deriving Chronic HHBP for General Population = [cPAD (mg/kg bw/day) x 1000 (µg/mg) x 0.2 RSC ] / 0.0338 (L/kg/day) DWI-BW ratio; Formula for deriving Chronic HHBP for Females 13-49 Years = [cPAD (mg/kg bw/day) x 1000 (µg/mg) x 0.2 RSC ] / 0.0354 (L/kg/day) DWI-BW ratio, and RSC = Relative Source Contribution assumed as 20%

c Where there is no value, refer to the document for the cancer classification and quantification.

d No value denotes that carcinogenic quantification is not applicable and therefore, no carcinogenic HHBP is determined.

e Formula for deriving carcinogenic HHBP (ppb) = [10-6 or 10-4/Drinking Water Unit Risk (ppb-1), where Drinking Water Unit Risk (ppb-1) = [CSF (per mg/kg/day) x 0.0338 (L/kg/day) adult DWI-BW ratio]/[1000 (µg/mg)]

f Represents the lowest benchmarks for the lifestage/population evaluated.

g Pesticide has no current registrations for food-use

h Pesticide is now classified as non-food use; benchmarks are based on tox data from 2017 HHBP update, using 2021 updated exposure factors.

i Pesticide was reevaluated by OPP with updated exposure pattern information demonstrating that no effects were seen at doses relevant for human health risk assessment; benchmarks were derived from 2017 OPP toxicity values using updated 2021 exposure factors.

j Mancozeb’s cancer risk is calculated by estimating exposure to mancozeb-derived ETU and using the ETU cancer potency factor (Q1*) of 6.01 x 10 -2 (mg/kg/day)-1

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Last updated on January 15, 2025
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