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CDX Risk Evaluation Rule User Guide - Primary Authorized Official

This document presents the user guide for the Office of Pollution Prevention and Toxics (OPPT) Risk Evaluation Rule application submission process. This document is the user guide for the Primary Authorized Official (AO) of the Risk Evaluation Rule application.

The Risk Evaluation Rule application is the electronic, web-based tool provided by the United States Environmental Protection Agency (EPA) for the submission of Risk Evaluation data and responses to FR Notices. As a Primary AO, you can create, modify, and/or submit a Manufacturer Risk Evaluation request, EPA Initiated Risk Evaluation, and an Initial Response. You can also pay invoices and receive EPA communications. You can also delete request and responses, submit a Withdrawal Request, create amendments, and download the Copy of Record (CoR).

For questions concerning the Toxic Substances Control Act (TSCA) Risk Evaluation software requirements, please contact the Central Data Exchange (CDX) Help Desk at helpdesk@epacdx.net or call 1-888-890-1995 between the hours of 8 am - 6 pm Eastern Standard Time (EST).

  • CDX Risk Evaluation User Guide - Primary Authorized Official (pdf) (5.57 MB)

TSCA Administration Fees

  • TSCA Fee Amounts
  • TSCA Fee-Triggering Events
  • TSCA Fees Rule Summary
  • TSCA Fees and Small Businesses
Contact Us About TSCA Administrative Fees
Contact Us to ask a question, provide feedback, or report a problem.
Last updated on March 12, 2025
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