Society of Toxicology (SOT) 2026 Conference

EPA Research at SOT | 2026

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EPA Presentations
EPA Posters
SOT Overview

EPA Presentations and Sessions

Day/Time (local)	Location	EPA Presenter	Session	Title (Hyperlinks are directed to SOT Online Planner)
Sunday, March 22 8:25-8:50 a.m.	Ballroom 6C	Villeneuve, Dan	CE Course: Systematic Methods for AOP Development and Application: New Technologies and Tools	The Evolution of Best Practices for the Development and Description of AOPs Suitable to Support Regulatory Application of New Approach Methodologies
Sunday, March 22 2:30-3:00 p.m.	Ballroom 6E	Akerman, Greg	CE Course: Rethinking Carcinogenicity Assays in the 21st Century: Testing a Functionality Framework	Carcinogen Risk Assessment: Beyond Conventional Guidelines-New Approaches
Sunday, March 22 4:00-4:20 p.m.	Ballroom 6E	Luz, Tony	CE Course: Rethinking Carcinogenicity Assays in the 21st Century: Testing a Functionality Framework	Navigating TSCA Regulations: TSCA and the ReCAAP Framework
Monday, March 23 11:20-11:50 a.m.	Ballroom 6C	Phelps, Drake	Symposium Session: Developmental PFAS Toxicity: Leveraging Zebrafish as a Model for Phenotypic, ’Omics, and Organ-Level Studies	Zebrafish Developmental Screening of a PFAS Chemical Library
Monday, March 23 3:20-3:40 p.m.	Exhibit Hall B	Gwinn, Maureen	Tiny Tox Talk	Meet the Director: US EPA/OASES
Monday, March 23 4:00-4:20 p.m.	Exhibit Hall B	Beck, Nancy	Tiny Tox Talk	Meet the Director: EPA Office of Chemical Safety and Pollution Prevention
Tuesday, March 24 8:05-8:30 a.m.	Room 8	Druwe, Ingrid	Workshop Session: The Quality Awakens: New Frontiers in the Appraisal of In Vitro Mechanistic Study Quality/Reliability	Bridging Biology and Risk: How US EPA Program Offices Apply In Vitro Data to Modernize Chemical Evaluations
Tuesday, March 24 8:00-10:45 a.m.	Ballroom 6D	Stoker, Tammy	Symposium Session: Co-chair and Panel Discussion	It’s Time to OVARY-Act: New Insights into the Effects of EDCs on Ovarian Function
Tuesday, March 24 4:30-6:00 p.m.	Room 1B	Wehmas, Leah	Roundtable Session: Co-Chair & Panel QA	Toward a New Paradigm: Can Mechanistic In Vivo Studies Replace Traditional DART Guideline Studies?
Wednesday, March 25 9:35-10:05 a.m.	Ballroom 6F	Wetmore, Barbara	Symposium Session: NAM In Vitro Assessment of Intestinal Metabolism to Inform PBK Modeling of Bioavailability and Systemic Exposure	Evaluating Contribution of Intestinal Toxicokinetic Features on Bioavailability Estimation

EPA Posters

See these posters in person at the SOT Annual Meeting or view online at the links below. Hyperlinks will exit the site. Please allow a moment for FigShare to load the virtual poster.

Monday, March 23

Time	Section Title	EPA Presenter	Title (Hyperlinks are directed to FigShare to display virtual poster)
9:15-11:45 AM	Risk Assessment I	Schumacher, Kelly	Evaluating New Chemicals Under the Toxic Substances Control Act (TSCA): Application of US EPA’s ChemInformatics Modules for Identification of Information for Human Health Risk Assessment
9:15-11:45 AM	Risk Assessment I	Hoer, Daniel	Skip to Recipe: the importance of food disaggregation in performing lifestage-specific dietary exposure assessments
9:15-11:45 AM	Risk Assessment I	Salazar, Keith	Application of the Threshold of Toxicological Concern (TTC) to Evaluate New Chemicals under the Toxic Substances Control Act (TSCA)
9:15-11:45 AM	Risk Assessment I	Mutlu, Esra	A Human Health Risk Assessment Approach for Evaluating Carbon Nanotubes under the Toxic Substances Control Act (TSCA)
9:15-11:45 AM	Risk Assessment I	Sasidharan, Abhilash	Utilizing Toxicokinetic and Mode of Action Information to Evaluate the Human Relevance of Ovarian Toxicity Data for 1,3-Butadiene
9:15-11:45 AM	NAMs: General	Villeneuve, Daniel	Reproducibility of points of departure derived from high throughput transcriptomic assays with four species of aquatic organisms
9:15-11:45 AM	NAMs: General	Nash, Mackenzie	Transcriptomic Points of Departure from Whole vs Targeted Transcriptome Sequencing
9:15-11:45 AM	NAMs: General	Brunner, Rachel	Implementation of a New Approach Methods (NAMs)-based Framework to Evaluate Skin Irritation of New Chemicals under TSCA
9:15-11:45 AM	NAMs: General	Tennant, Alan	Longitudinal high-throughput phenotypic profiling using live-cell staining in U-2 OS cells over a 72-hour period
1:45-4:15 PM	Air Pollution Tox	Yoo, Brendan	HEPA Filtration Modifies Pulmonary Responses to Episodic Eucalyptus Smoke Exposure in Male Long-Evans Rats [Only available in-person]
1:45-4:15 PM	Endocrine Toxicology	Casciano, Grace	Phenotypic and transcriptomic consequences of deiodinase 3a, 3b mutations in developing zebrafish
1:45-4:15 PM	Endocrine Toxicology	Abedini, Jaleh	Developing A Curated Resource of Rodent Pubertal Studies in Support of the US EPA Endocrine Disruptor Screening Program (EDSP)
1:45-4:15 PM	Reproductive Toxicology 1	Stocker, Tammy	Novel detection of legacy and emerging PFAS in the follicular fluid of IVF patients from North Carolina

Tuesday, March 24

Time	Section Title	EPA Presenter	Title (Hyperlinks are directed to FigShare to display virtual poster)
9:15-11:45 AM	PFAS I	DeVito, Michael	Subchronic 90-Day Oral Toxicity Study With Perfluoropentanoic Acid In Sprague Dawley Rats
9:15-11:45 AM	NAMs: Computational	Staub, Ryan	Defining Best Practices for the Use of Sequence Alignment to Predict Across Species Susceptibility to Inform Taxonomic Domain of Applicability Descriptions in the Adverse Outcome Pathway Wiki
1:45-4:15 PM	NAMs: In Vitro III	Jackson, Thomas	Impacts of Exposure Method and Cell Type on Transcriptomic Concentration-Response Curves during Toxicological Screening of Respiratory Irritants
1:45-4:15 PM	Neurotoxicity: General	Feshuk, Madison	Curating Developmental Neurotoxicity in the Toxicity Reference Database (ToxRefDB)
1:45-4:15 PM	NAMs: In Vitro III	Sumner, Catherine	Evaluating Effects of Varying Serum Levels on In Vitro Disposition (IVD) and Partitioning of Per- and Polyfluoroalkyl Substances (PFAS) in Human Cell Models
1:45-4:15 PM	NAMs: In Vitro III	Jurgelewicz, Amanda	Exploring the Use of Cell Painting and Transcriptomics in a Battery of Human Cell Lines for Bioactivity-Based Chemical Prioritization
1:45-4:15 PM	NAMs: In Vitro III	Leonard, Jeremy	Use of Data Derived Extrapolation Factors to Reduce Uncertainty in Organophosphate Human Health Risk Assessments
1:45-4:15 PM	NAMs: In Vitro III	Willis, Clinton	Screening Level Assessment of 1470 ToxCast Chemicals Across Nine Biologically Diverse Human Cell Lines Using the Cell Painting Assay
1:45-4:15 PM	NAMs: In Vitro III	Murray, Jessica	Evaluating Respiratory Irritants using New Approach Methods: Harmonizing Key Study Design Variables for Air-Liquid Interface and Direct Liquid Application Exposures
1:45-4:15 PM	NAMs: In Vitro III	Sadrpour, Parisa	Comparative Predictivity of Estrogen-Dependent Cell Proliferation Assays to In Vitro/In Vivo Reference Data
1:45-4:15 PM	NAMs: In Vitro III	Pereira, Kenzie	Predictivity Assessment of the Human Thyroid Microtissue Assay
1:45-4:15 PM	Carcinogenesis I	Luz, Anthony	Mode of Action Analysis of the Tumor Triad Induced by DEHP

Wednesday, March 25

Time	Section Title	EPA Presenter	Title (Hyperlinks are directed to FigShare to display virtual poster)
9:15-11:45 AM	Computational Toxicology	Feshuk, Madison	Exploring ToxCast: Enhancing Public Access to Targeted Bioactivity Screening Data
9:15-11:45 AM	Computational Toxicology	Chen, Yichang (Ian)	Leveraging Machine Learning for Efficient Prediction of Acute Inhalation Toxicity of Environmental Chemicals
9:15-11:45 AM	Ecotoxicology	Baettig, Camille	Estrogenic activity of PFAS with variable length and structure using human cell bioassays and rainbow trout (Oncorhynchus mykiss) liver slice assays
9:15-11:45 AM	Ecotoxicology	Ankley, Phillip	Xenometabolome Profiling of Structurally Diverse PFAS in Rainbow Trout Oncorhynchus mykiss Liver Slices
9:15-11:45 AM	Regulation/Policy	Louden, Ruthanne	EPA's Implementation of the Endocrine Disruptor Screening Program (EDSP) Near-Term Strategies
1:45-4:15 PM	ADME/TK II	Tan, Cecilia	Beyond the kinetically derived maximum dose: a holistic view of nonlinear pharmacokinetics
1:45-4:15 PM	ADME/TK II	Sims, Jaylen	Cross-Species Comparisons of Plasma Binding and Metabolic Clearance Data for Use in New Approach Methods
1:45-4:15 PM	ADME/TK II	Kapraun, Dustin	MCSimMod: Updates and Improvements to an R Package for Implementation and Application of PBPK Models
1:45-4:15P	Late Breaking 1	Barbo, Nadia	A High-Throughput Imaging-Based Assay for Quantifying Phagocytosis in Neutrophil[1]and Macrophage-Like Cell Lines
1:45-4:15 PM	Late Breaking 1	Caty, Stephanie	Application of high-content imaging to detect chemically mediated changes in neutrophil counts in transgenic zebrafish larvae
1:45-4:15 PM	Late Breaking 2	Truong, Kimberly	Bayesian Network Modeling for Developmental Neurotoxicity in vitro data
1:45-4:15 PM	Late Breaking 6	Scherer, Meredith	Evaluation of QSPR Models for Key Toxicokinetic Parameters in Screening Level Risk Assessment

Overview

EPA scientists are participating in the 2026 Society of Toxicology (SOT) Annual Meeting and ToxExpo from March 22-25 in San Diego, CA. Advances in EPA's toxicology research will be featured at SOT sessions, symposia, workshops, platform discussions, informational sessions, and poster sessions. SOT provides a forum to discuss and disseminate information about this research to the scientific community.

EPA scientists serve in leadership roles in SOT such as officers and chairpersons, leading and participating in continuing education courses and providing scientific presentations during plenary sessions as keynote speakers.