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PRN 98-10: Notifications, Non-Notifications and Minor Formulation Amendments

Additional Information
  • Expedited Review for Products Adding Residual Efficacy Claims

On December 31, 2025, EPA released for public comment proposed updates to Pesticide Registration Notice (PRN) 98-10, “Notifications, Non-notifications and Minor Formulation Amendments.” The new draft would provide updated guidance to registrants submitting minor modifications to a registration that do not require extensive EPA review. These modifications do not have any substantive impact on the use or safety of a pesticide. The proposed changes will not impact any procedures for the review of information related to environmental or human health.  

View a prepublication of the Federal Register notice:  FRN-5992-03-OCSPP Prepub (pdf) (1.04 MB)

On September 15, 2021, the Agency announced the termination of the May 11, 2020, temporary amendment effective September 15, 2022, and that any changes made using the temporary amendment must be made permanent by Sept. 15, 2022. The Agency requires additional time to complete the review and approval of the notifications and amendments to make these changes permanent and is therefore extending the deadline to March 15, 2023. 
 

  • Extension of The Termination Date For The Temporary Amendment to Pesticide Registration (PR) Notice 98-10: Notice to Manufacturers, Producers, Formulators and Registrants of Pesticide Products (pdf) (278.36 KB)
  • PRN 98-10: Notifications, Non-Notifications and Minor Formulation Amendments (pdf) (242.97 KB)
  • Temporary Amendment To PRN 98-10 (pdf) (71.64 KB, May 11, 2020)
  • Termination of The Temporary Amendment to Pesticide Registration (PR) Notice 98-10: Notice to Manufacturers, Producers, Formulators and Registrants of Pesticide Products (pdf) (312.09 KB)

Pesticide Registration

  • About Pesticide Registration
  • Electronic Submission of Applications
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  • — Antimicrobial Registration
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Contact Us about Pesticide Registration
Contact Us about Pesticide Registration to ask a question, provide feedback, or report a problem.
Last updated on December 31, 2025
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