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  2. Pollinator Protection

EPA-registered Pesticide Products Approved for Use Against Varroa Mites in Bee Hives

EPA is committed to helping beekeepers combat Varroa mites. Varroa mites are parasites that feed on developing bees, leading to brood mortality and reduced lifespan of worker bees. They also transmit numerous honeybee viruses. The health of a colony can be critically damaged by an infestation of Varroa mites. Once infested, if left untreated, the colony will likely die. By expediting the approval of pesticides that target Varroa mites and publishing information about the products, EPA is helping beekeepers deal with these challenging pests. EPA is continuing to work with the beekeeping community to register new tools for managing beehive pests and working with our federal and local partners to advance valuable research

The pesticide products listed on this page are registered by EPA at the federal level for use against Varroa mites. Rotating products to combat Varroa mites is an important tactic to prevent resistance development and to maintain the usefulness of individual pesticides. Beekeepers are encouraged to check with their state pesticide regulatory agencies to determine the regulatory status of the products in the individual states. Find state pesticide regulatory agencies. 

In January 2023 EPA issued an advisory to clarify what pesticide products and active ingredients are registered to control varroa mites in beehives, what tolerances or exemption under the Federal Food Drug and Cosmetic Act (FFDCA) apply to those products, and how the Agency views the use of unregistered products to treat beehives for one's own personal use. Please read EPA's advisory for beekeepers for additional information.

Primary registered products in the list have 2-part EPA registration numbers and are listed in bold. Distributor products have a 3-part EPA registration number, with the first two numbers reflecting the primary registered product’s registration number. Distributors may market their products under different names, but the formulations and uses are identical to the primary registered.

EPA Registration NumberPrimary Brand/Product NameActive Ingredient (% Active Ingredient)
100908-1MGB2X5G Stripsl-glutamic Acid (25.1%)
2724-406ZOECON RF-318 APISTAN STRIPFluvalinate (10.25%)
2724-406-62042APISTAN ANTI-VARROA MITE STRIPSFluvalinate (10.25%)
2724-406-79671APISTAN VARROA CONTROL STRIPS FOR BEESFluvalinate (10.25%)
11556-138CHECKMITE+ BEE HIVE PEST CONTROL STRIPCoumaphos (10%)
11556-138-61671CHECKMITE+ BEE HIVE PEST CONTROL STRIPCoumaphos (10%)
73291-1API LIFE VARThymol (74.09%)
Oil of Eucalyptus (16%)
Menthol (3.73%)
73291-2API-BIOXALOxalic Acid Dihydrate (97%)
75710-2MITE-AWAY QUICK STRIPSFormic Acid (46.7%)
75710-3FORMIC PROFormic Acid (42.25%)
79671-1APIGUARDThymol (25%)
83623-2HOPGUARD3Hop Beta Acids Resin (16%)
87243-1APIVARAmitraz (3.33%)
87243-4AMIFLEXAmitraz (2%)
94413-3VARROXSANOxalic Acid Dihydrate (18.42%)
94424-1ORGANISHIELD SUCROSE OCTANOATE (40%)Sucrose Octanoate (40%)
101743-2EZ-OX TABLETSOxalic Acid Dihydrate (97%)

Pollinator Protection

  • Pollinator Health Concerns
  • — Colony Collapse Disorder
  • — Factors Affecting Pollinator Heath
  • — Risk Assessment
  • — EPA Actions to Protect Pollinators
  • — Partners in Pollinator Protection
  • What You Can Do
  • — Report Bee Kills
  • — Best Management Practices
Contact Us about Pollinator Protection
Contact Us about Pollinator Protection to ask a question, provide feedback, or report a problem.
Last updated on June 26, 2025
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