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Safer Chemicals Research Grants

Safer Chemicals

EPA funds safer chemical research grants supporting the development of innovative science to support safer, more sustainable use of chemicals in consumer products and chemicals used for other purposes such as pesticides. Using safer, more sustainable chemicals will help to better protect human and environmental health, including sensitive populations like children, elderly and endangered species. 

All forms necessary for completing an application are referenced in the funding opportunity and available to download online. Funding Opportunities: How to Apply and Required Forms


Open Funding Opportunities

There are no open Funding Opportunities

Recent Funding Opportunities

These funding opportunities are closed for applications. Award recipients have not been announced.

  • Advancing Sustainable Chemistry

Open Grants

These Safer Chemicals research grants are currently open or have been awarded within the past ten years.

  • Developing and Demonstrating Nanosensor Technology to Detect, Monitor and Degrade Pollutants (FY23)
  • Developing and Demonstrating Nanosensor Technology to Detect, Monitor, and Degrade Pollutants (FY22)
  • Development of Innovative Approaches to Assess the Toxicity of Chemical Mixtures 
  • Assessment Tools for Biotechnology Products
  • Advancing Actionable Alternatives to Vertebrate Animal Testing for Chemical Safety Assessment
  • Addressing Environmental Concerns in Vieques, Puerto Rico Through Community Participatory Research

Closed Grants

  • Advancing Toxicokinetics for Efficient and Robust Chemical Evaluations
  • Systems-Based Research for Evaluating Ecological Impacts of Manufactured Chemicals
  • Organotypic Culture Models for Predictive Toxicology Center
  • New Methods in 21st Century Exposure Science
  • Susceptibility and Variability in Human Response to Chemical Exposure
  • EPA/NSF Networks for Characterizing Chemical Life Cycle (NCCLCs)
  • Development and Use of Adverse Outcome Pathways that Predict Adverse Developmental Neurotoxicity
  • Developing High-Throughput Assays for Predictive Modeling of Reproductive and Developmental Toxicity Modulated Through the Endocrine System or Pertinent Pathways in Humans and Species Relevant to Ecological Risk Assessment
  • Computational Toxicology: Biologically-Based Multi-Scale Modeling
  • Increasing Scientific Data on the Fate, Transport and Behavior of Engineered Nanomaterials in Selected Environmental and Biological Matrices
  • Environmental Behavior, Bioavailability and Effects of Manufactured Nanomaterials - Joint US – UK Research Program

For a complete listing of EPA Safer Chemicals Research Grants: Safer Chemicals Research Projects.


Stay Current on Research Funding Opportunities & Events

Sign up for EPA’s Office of Science, Advisor, Policy & Engagement listserv to receive announcements on new funding opportunities, upcoming research meetings and webinars, and special announcements. Research Grants Listserv

Featured Safer Chemicals Resources

  • Safer Chemicals Research
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  • Substances and Toxics Science
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Last updated on May 20, 2025
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