Skip to main content
U.S. flag

An official website of the United States government

Here’s how you know

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

HTTPS

Secure .gov websites use HTTPS
A lock (LockA locked padlock) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

    • Environmental Topics
    • Air
    • Bed Bugs
    • Cancer
    • Chemicals, Toxics, and Pesticide
    • Emergency Response
    • Environmental Information by Location
    • Health
    • Land, Waste, and Cleanup
    • Lead
    • Mold
    • Radon
    • Research
    • Science Topics
    • Water Topics
    • A-Z Topic Index
    • Laws & Regulations
    • By Business Sector
    • By Topic
    • Compliance
    • Enforcement
    • Laws and Executive Orders
    • Regulations
    • Report a Violation
    • Environmental Violations
    • Fraud, Waste or Abuse
    • About EPA
    • Our Mission and What We Do
    • Headquarters Offices
    • Regional Offices
    • Labs and Research Centers
    • Planning, Budget, and Results
    • Organization Chart
    • EPA History

Breadcrumb

  1. Home
  2. Scientific Leadership
  3. Human Subjects Research

Human Studies Review Board

The Human Studies Review Board (HSRB) is a federal advisory committee that operates in accordance with the provisions of the Federal Advisory Committee Act (FACA), 5 U.S.C. § 10 . The HSRB is required by 40 CFR Part 26 to review and comment on all proposed and completed third-party research (i.e. ., research that is not conducted or sponsored by the Federal government) involving intentional human subject exposure that is subject to the coverage of EPA’s regulations (see subparts K-L).

Key Links

  • History and Focus 

  • Current Membership

  • Meetings and Minutes

The HSRB provides advice, information, and recommendations to EPA on issues related to scientific and ethical aspects of human subjects research. The major objectives of the HSRB are to provide advice and recommendations on: (1) Research proposals and protocols that include human subjects; and (2) reports of completed research with human subjects. The HSRB reports to the EPA Administrator through EPA's Human Subject Research Review Official (HSRRO). 

HSRB Call for Nominations

The U.S. Environmental Protection Agency (EPA) is seeking nominations for technical experts to serve on its Human Studies Review Board (HSRB). In this new recruitment effort, we are seeking members with expertise in the areas of toxicology, bioethics and statistics. Members may serve terms up to six years. Nominations are now open and will close May 30, 2025. Individuals and organizations can nominate themselves or others by completing the nomination form below.

2025 U.S. EPA Human Studies Review Board (HSRB) Nomination Form

Federal Register Notice

Scientific Leadership

  • Risk Assessment Support
  • Human Subjects Research
    • About Human Subjects Research
    • For EPA Grantees Proposing Human Subjects Research
  • Peer Review
  • Public Access
Contact Us about Programs of the Office of the Science Advisor
Contact Us to ask a question, provide feedback, or report a problem.
Last updated on April 30, 2025
  • Assistance
  • Spanish
  • Arabic
  • Chinese (simplified)
  • Chinese (traditional)
  • French
  • Haitian Creole
  • Korean
  • Portuguese
  • Russian
  • Tagalog
  • Vietnamese
United States Environmental Protection Agency

Discover.

  • Accessibility Statement
  • Budget & Performance
  • Contracting
  • EPA www Web Snapshot
  • Grants
  • No FEAR Act Data
  • Plain Writing
  • Privacy
  • Privacy and Security Notice

Connect.

  • Data
  • Inspector General
  • Jobs
  • Newsroom
  • Regulations.gov
  • Subscribe
  • USA.gov
  • White House

Ask.

  • Contact EPA
  • EPA Disclaimers
  • Hotlines
  • FOIA Requests
  • Frequent Questions
  • Site Feedback

Follow.