TRI-Listed Chemicals
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Note: methyl mercaptan and 2,2-dibromo-3-nitrilopropionamide are under administrative stays and are not currently reportable.
In general, chemicals covered by the Toxics Release Inventory (TRI) Program are those that cause one or more of the following:
- Cancer or other chronic human health effects
- Significant adverse acute human health effects
- Significant adverse environmental effects
The current TRI toxic chemical list contains 799 individually listed chemicals and 33 chemical categories.
- Chemical list changes: 1987-2024
- TRI chemicals classified as OSHA carcinogens
- TRI chemicals of special concern
- TRI chemicals and other EPA regulatory programs
- About the toxicity of TRI chemicals
Chemical List Changes: 1987-2024
EPA makes changes to the TRI chemical list through EPA-initiated review and through the chemical petitions process. As a result, the TRI list of reportable toxic chemicals can vary from year to year.
Recent TRI Chemical List Changes
- Under the automatic listing provisions of the 2020 National Defense Authorization Act:
- Seven PFAS were added for reporting year 2024. Reporting forms on these chemicals are due July 1, 2025, for 2024 data if TRI reporting thresholds are met.
- Nine PFAS were added for reporting year 2025. Reporting forms on these chemicals are due July 1, 2026, for 2025 data if TRI reporting thresholds are met.
- See Addition of Certain PFAS to the TRI by the National Defense Authorization Act for more information.
- In July 2023, EPA added a category of diisononyl phthalate (DINP) chemicals to the TRI list. The first reporting forms for this category are due July 1, 2025, for 2024 data if TRI reporting thresholds are met.
- In November 2022, EPA added 12 chemicals in response to a petition submitted under Section 313(e) of EPCRA. Reporting forms on these chemicals are due July 1, 2024, for 2023 data if TRI reporting thresholds are met.
All TRI Chemical List Changes (pdf) : Record of all additions to and deletions from the TRI chemical list. Indicates the first or last reporting year for each chemical.
TRI Chemicals Classified as OSHA Carcinogens
Basis of TRI OSHA Carcinogen Designation (pdf) : Lists chemicals considered to be carcinogens under the requirements adopted from the Occupational Safety and Health Administration (OSHA) (see 40 CFR §372.38(a)) and the basis for the classifications.
TRI Chemicals of Special Concern
EPA has classified some TRI chemicals and chemical categories as “chemicals of special concern.” These include PBT (persistent bioaccumulative toxic) chemicals and PFAS (per/polyfluoroalkyl substances). These are of particular concern because they remain in the environment for long periods of time, are not readily destroyed, and build up or accumulate in body tissue.
- Addition of Certain PFAS to the TRI List
- TRI PBT-Related Rulemakings
- Dioxin and Dioxin-like Compounds Toxic Equivalency Information Final Rule
TRI Chemicals and Other EPA Regulatory Programs
Consolidated "List of Lists": EPA prepared this document to help facilities determine, for a specific chemical, whether they may be subject to reporting requirements under:
- Emergency Planning and Community Right-to-Know Act (EPCRA) - Section 302 and 313
- Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA or "Superfund")
- Resource Conservation and Recovery Act (RCRA)
- Clean Air Act - Section 112(r)
About the Toxicity of TRI Chemicals
- TRI-Chemical Hazard Information Profiles (TRI-CHIP): TRI's searchable database system contains hazard information for TRI chemicals. Among other features, users can search for toxicity information from multiple information sources and identify TRI chemicals associated with a particular critical adverse human health effect.
- Agency for Toxic Substances and Disease Registry (ATSDR) ToxFAQs: ToxFAQs is a series of printable fact sheets that answer the most frequently asked questions about exposure to hazardous substances and the effects of exposure on human health. Many of these substances are also TRI chemicals. Available in multiple languages.
- Right-to-Know Hazardous Substance Fact Sheets: The New Jersey Department of Health's library includes information on more than 1,600 hazardous substances, many of which are TRI chemicals. Available in English and Spanish.
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Toxic Chemicals Added Under 1994 Chemical Expansion: Summary hazard information on the 286 chemicals that were added to the TRI in 1994.