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  2. TRI National Analysis

Chemical Profiles

This section profiles Toxics Release Inventory (TRI) chemicals of interest to the public, the Environmental Protection Agency (EPA), lawmakers, and industry. These chemical profiles include:

  • Chemicals designated by the TRI Program as chemicals of special concern. TRI chemicals of special concern include chemicals that are not only toxic, but also break down slowly in the environment and build up (bioaccumulate) in organisms throughout the food web. TRI reporting thresholds for these chemicals are either 10 pounds or 100 pounds, which is much lower than the reporting threshold for most TRI chemicals. For dioxin and dioxin-like compounds, the reporting threshold is even lower at 0.1 gram. The chemicals of special concern covered in this section are lead, mercury, dioxin and dioxin-like compounds, and per- and polyfluoroalkyl substances (PFAS).
  • Chemicals that are classified as carcinogens. The TRI chemical list includes over 200 chemicals and chemical categories that are defined as carcinogens (agents that can cause cancer) under the Occupational Safety and Health Administration (OSHA) Hazard Communication Standard (29 CFR 1910.1200). The carcinogens covered in this section are ethylene oxide, and the combined group of all TRI chemicals classified as carcinogens.

You can generate a fact sheet for any TRI chemical using TRI Explorer. The full list of TRI chemicals can be found here.


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This page was published in August 2025 and uses the 2023 TRI National Analysis dataset made public in TRI Explorer in October 2024.

TRI National Analysis

  • TRI Program Home
  • Introduction
    • TRI Data Considerations
  • Pollution Prevention
    • Source Reduction Activities
    • Source Reduction Activities by Chemical & Industry
    • Measuring the Impact of Source Reduction
    • Green Chemistry & Engineering Activities
    • Reported Barriers to Source Reduction
    • Source Reduction Activities by Parent Company
  • Waste Management
    • Trends in Waste Management
    • Waste Management by Chemical & Industry
    • Non-Production-Related Waste Managed
    • Waste Managed by Parent Company
  • Releases of Chemicals
    • Trends in Releases
    • Releases by Chemical & Industry
    • Air Releases
      • Air Releases by Chemical & Industry
    • Water Releases
      • Water Releases by Chemical & Industry
    • Land Disposal
      • Land Disposal by Chemical & Industry
  • Chemical Profiles
    • Lead
    • Mercury
    • Dioxins
    • Ethylene Oxide
    • Carcinogens
    • PFAS
  • Sector Profiles
    • Manufacturing Sectors
      • Manufacturing Waste Management Trend
    • Chemical Manufacturing
      • Chemical Manufacturing Waste Management Trend
    • Automotive Manufacturing
      • Automotive Manufacturing Waste Management Trend
    • Wood Products Manufacturing
      • Wood Products Waste Management Trend
    • Electric Utilities
      • Electric Utilities Waste Management Trend
    • Federal Facilities
      • Federal Facilities by Industry
      • Waste Management by Federal Facilities
  • Where You Live
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    • States & Metropolitan Areas
    • Watersheds
    • Tribal Communities
  • TRI Connections
  • Data Dashboard
  • National Analysis Archive
Contact Us About the TRI National Analysis
Contact Us About the TRI National Analysis to ask a question, provide feedback, or report a problem.
Last updated on August 20, 2025
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